Styrene

Styrene

SCHEMBL5832166

C=CC(=O)OCCCC.C=Cc1ccccc1.CC(C)COC(=O)/C=C\C(=O)O

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 7/20 0.52
TSHR P16473 3/20 0.48
HPGD P15428 1/20 0.48
ATM Q13315 1/20 0.43
APP P05067 2/20 0.40
THRB P10828 1/20 0.40
TDP1 Q9NUW8 2/20 0.39
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL5832170 1.00 HCAR2 (0.52) HCAR2TSHRHPGDATMAPP
Butyl Fumarate SCHEMBL3956264 0.92 HCAR2 (0.61) HCAR2TSHRHPGDATMAPP
Butyl Fumarate SCHEMBL3956267 0.92 HCAR2 (0.61) HCAR2TSHRHPGDATMAPP
Styrene SCHEMBL5698364 0.90 TSHR (0.59) HCAR2TSHRHPGDATMAPP
Styrene SCHEMBL5698366 0.90 TSHR (0.59) HCAR2TSHRHPGDATMAPP
Ethyl Fumarate SCHEMBL250119 0.89 HCAR2 (0.57) HCAR2TSHRHPGDATMAPP
Butyl Fumarate SCHEMBL10908635 0.89 HCAR2 (0.57) HCAR2TSHRHPGDATMAPP
Butyl Fumarate SCHEMBL2164919 0.89 HCAR2 (0.67) HCAR2TSHRHPGDATMAPP
Butyl Fumarate SCHEMBL2164913 0.89 HCAR2 (0.67) HCAR2TSHRHPGDATMAPP
Styrene SCHEMBL7589392 0.89 TSHR (0.58) HCAR2TSHRHPGDTHRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060283782-A1 Toner and image forming apparatus using the same SEIKO EPSON CORPORATION 2006-12-21 US disclosed
US-20060275687-A1 Toner and image forming apparatus using the same SEIKO EPSON CORPORATION 2006-12-07 US disclosed
US-20060088780-A1 Toner and image forming apparatus using the same SEIKO EPSON CORPORATION 2006-04-27 US disclosed
US-7018762-B2 Toner and image forming apparatus using the same SEIKO EPSON CORPORATION (JP) 2006-03-28 US disclosed
US-20040265720-A1 Toner and image forming apparatus using the same SEIKO EPSON CORPORATION 2004-12-30 US disclosed
US-6821701-B2 Toner and image forming apparatus SEIKO EPSON CORPORATION (JP) 2004-11-23 US disclosed
US-6811942-B2 SPECIFIED EXTERNAL ADDITIVE COATING RATIO OF TONER PARTICLES OF GIVEN DIAMETERS; ?OIL-LESS FUSING? AND LONGER-LIFE DEVELOPING UNIT SEIKO EPSON CORPORATION (JP) 2004-11-02 US disclosed
US-6686110-B2 HIGH FLUIDITY HEXAMETHYLENE DISILAZANE SURFACE TREATED SILICA; CONTACTOR DURABILITY; LOW TEMPERATURE FIXING SEIKO EPSON CORPORATION (JP) 2004-02-03 US disclosed
US-20030207191-A1 In a toner T of the present invention, the liberated mother particle ratio is set to be 10% or less and the liberated silica particle ratio is set to be 0.2-10%, thereby reducing the possibility that the liberated mother particles 18' and SEIKO EPSON CORPORATION 2003-11-06 US disclosed
US-6605401-B2 Silica (SiO2) on surfaces of mother particles to improve the fluidity and electrification characteristics; reliably preventing occurrence of filming and furthermore extending the lifetime thereof SEIKO EPSON CORPORATION (JP) 2003-08-12 US disclosed
US-20030077532-A1 Toner and development unit and image forming apparatus using the same SEIKO EPSON CORPORATION 2003-04-24 US disclosed
US-20030003386-A1 Toner and image forming apparatus SEIKO EPSON CORPORATION 2003-01-02 US disclosed
US-20020164536-A1 Toner and image forming apparatus SEIKO EPSON CORPORATION 2002-11-07 US disclosed
EP-1248159-A2 Toner and image forming apparatus Seiko Epson Corporation (JP) 2002-10-09 EP disclosed
EP-1248157-A2 Toner and image forming apparatus Seiko Epson Corporation (JP) 2002-10-09 EP disclosed
EP-1220043-A2 Toner and image forming apparatus using the same Seiko Epson Corporation (JP) 2002-07-03 EP disclosed
US-6358654-B1 TONER PARTICLES AND JOINING SEIKO EPSON CORPORATION (JP) 2002-03-19 US disclosed
US-6146802-A INCLINATION OF SAID MOTHER PARTICLES) OF AN APPROXIMATION STRAIGHT LINE OBTAINED BY APPROXIMATING DISTRIBUTION OF PARTICLE SIZES OF SAID EXTERNAL ADDITIVES WITH RESPECT TO THE PARTICLE SIZES OF SAID MOTHER PARTICLES SEIKO EPSON CORPORATION (JP) 2000-11-14 US disclosed
EP-0977092-A2 Toner and development unit and image forming apparatus using the same SEIKO EPSON CORPORATION (JP) 2000-02-02 EP disclosed