Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CCR3 | P51677 | 1/20 | 0.31 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18242067 | 0.81 | GABRA1 (0.42) | GABRA1GABRB2MGLLCYP24A1MAPT | |
| SCHEMBL5330754 | 0.75 | GABRA1 (0.38) | GABRA1GABRB2MGLLCYP24A1MAPT | |
| SCHEMBL5892736 | 0.75 | GABRA1 (0.43) | GABRA1GABRB2MGLLCYP24A1MAPT | |
| SCHEMBL8371947 | 0.75 | GABRA1 (0.38) | GABRA1GABRB2MGLLCYP24A1MAPT | |
| SCHEMBL9541229 | 0.75 | TSHR (0.46) | MAPTNPSR1L3MBTL1MEN1LMNA | |
| SCHEMBL1149697 | 0.73 | GABRA1 (0.37) | GABRA1GABRB2MGLLCYP24A1MAPT | |
| SCHEMBL3314625 | 0.73 | CHAT (0.47) | GABRA1GABRB2MGLLCYP24A1MAPT | |
| SCHEMBL1283641 | 0.73 | GABRA1 (0.44) | GABRA1GABRB2MGLLCYP24A1MAPT | |
| SCHEMBL6546259 | 0.73 | CHAT (0.47) | GABRA1GABRB2MGLLCYP24A1MAPT | |
| SCHEMBL15563320 | 0.72 | POLB (0.37) | GABRA1GABRB2MGLLTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7009015-B2 | Silane compounds with an ortho-substituted aromatic ring directly attached to the silicon atom useful as electron donors in Ziegler-Natta catalysts; makes propylene polymers with high degree of stereoblocks | BASELL TECHNOLOGY COMPANY BV (NL) | 2006-03-07 | — | — | US | disclosed |