Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.33 |
| ▸ | CCR3 | P51677 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15563320 | 0.88 | POLB (0.37) | GABRA1GABRB2MGLLCYP2D6THRB | |
| SCHEMBL9248747 | 0.86 | LIPG (0.38) | GABRA1GABRB2CYP2D6MAPTLMNA | |
| SCHEMBL15563323 | 0.85 | MITF (0.35) | CYP2D6TRPA1ALDH1A1 | |
| SCHEMBL18242067 | 0.84 | GABRA1 (0.42) | GABRA1GABRB2MGLLCYP2D6MAPT | |
| SCHEMBL15563503 | 0.82 | CYP3A4 (0.42) | CYP2D6MAPTTHRB | |
| SCHEMBL8124003 | 0.80 | GABRA1 (0.42) | GABRA1GABRB2MAOA | |
| SCHEMBL15563655 | 0.80 | LIPG (0.49) | CYP2D6MAPTTHRB | |
| SCHEMBL15563138 | 0.79 | LIPG (0.51) | MAPTTHRB | |
| SCHEMBL5892736 | 0.78 | GABRA1 (0.43) | GABRA1GABRB2MGLLCYP2D6MAPT | |
| SCHEMBL8371947 | 0.78 | GABRA1 (0.38) | GABRA1GABRB2MGLLCYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690854-A1 | 1-PHENYL-IMIDAZOL-2-ONE BIPHENYLMETHYL COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1996-01-10 | — | — | EP | claimed |
| WO-2021107870-A1 | ANTIMICROBIAL AGENT, COATING FORMULATION, COMPOSITE SURFACE COATING AND METHODS OF PREPARING THE SAME | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2021-06-03 | — | — | WO | disclosed |
| US-10451967-B2 | Acid- and radical-generating agent and method for generating acid and radical | FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) | 2019-10-22 | — | — | US | disclosed |
| US-9802902-B2 | Antifungal compound | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2017-10-31 | — | — | US | disclosed |
| US-20170037013-A1 | ANTIFUNGAL COMPOUND | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2017-02-09 | — | — | US | disclosed |
| US-20160342084-A1 | ACID- AND RADICAL-GENERATING AGENT AND METHOD FOR GENERATING ACID AND RADICAL | FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) | 2016-11-24 | — | — | US | disclosed |
| US-9493424-B2 | Antifungal compound | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2016-11-15 | — | — | US | disclosed |
| US-20150203454-A1 | ANTIFUNGAL COMPOUND | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2015-07-23 | — | — | US | disclosed |
| WO-2014025314-A1 | An Antifungal Compound | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2014-02-13 | — | — | WO | disclosed |
| EP-1773853-A1 | MONOPHOSPHINE COMPOUNDS, TRANSITION METAL COMPLEXES THEREOF AND PRODUCTION OF OPTICALLY ACTIVE COMPOUNDS USING THE COMPLEXES AS ASYMMETRIC CATALYSTS | Sumitomo Chemical Company, Limited (JP) | 2007-04-18 | — | — | EP | disclosed |
| WO-2005121157-A1 | MONOPHOSPHINE COMPOUNDS, TRANSITION METAL COMPLEXES THEREOF AND PRODUCTION OF OPTICALLY ACTIVE COMPOUNDS USING THE COMPLEXES AS ASYMMETRIC CATALYSTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10451967-B2 | Acid- and radical-generating agent and method for generating acid and radical | CBR1, HAO2, CBR3 | GABRA1 924/4885GABRB2 2041/4885MGLL 2557/4885 |
| US-20160342084-A1 | ACID- AND RADICAL-GENERATING AGENT AND METHOD FOR GENERATING ACID AND RADICAL | CBR1, HAO2, CBR3 | GABRA1 924/4885GABRB2 2041/4885MGLL 2557/4885 |
| US-20150203454-A1 | ANTIFUNGAL COMPOUND | ERG28, DPM1, BAK1 | GABRA1 2089/4885GABRB2 2264/4885MGLL 3835/4885 |
| US-20170037013-A1 | ANTIFUNGAL COMPOUND | ERG28, DPM1, BAK1 | GABRA1 2089/4885GABRB2 2264/4885MGLL 3835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.