SCHEMBL5833071

SCHEMBL5833071

SCCNCc1ccc(Cl)nc1

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.53
GAA P10253 2/20 0.53
MAPT P10636 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
OXTR P30559 1/20 0.49
AVPR1A P37288 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.45
ALDH1A1 P00352 1/20 0.45
PLK1 P53350 1/20 0.45
KDM1A O60341 1/20 0.43
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
NLRP3 Q96P20 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5833308 0.90 KDM4E (0.50) KDM4EGAAMAPTL3MBTL1OXTR
SCHEMBL14044150 0.85 GAA (0.56) KDM4EGAAMAPTL3MBTL1OXTR
SCHEMBL9279836 0.85 GAA (0.63) KDM4EGAAMAPTL3MBTL1OXTR
SCHEMBL8011790 0.84 PLK1 (0.44) KDM4EGAAMAPTL3MBTL1OXTR
SCHEMBL29777000 0.82 KDM4E (0.53) KDM4EGAAMAPTL3MBTL1OXTR
SCHEMBL30493949 0.82 KDM4E (0.53) KDM4EGAAMAPTL3MBTL1OXTR
SCHEMBL5012154 0.82 KDM4E (0.53) KDM4EGAAMAPTL3MBTL1OXTR
SCHEMBL1797036 0.82 KDM4E (0.53) KDM4EGAAMAPTL3MBTL1OXTR
SCHEMBL4854056 0.82 KDM4E (0.53) KDM4EGAAMAPTL3MBTL1OXTR
SCHEMBL1633762 0.82 KDM4E (0.53) KDM4EGAAMAPTL3MBTL1OXTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5070431-A None JP disclosed
CN-103797008-B For the method preparing [3-[(6-chloro-3-pyridyl base) methyl]-2-Thiazolidine subunit] cyanamide 拜耳知识产权有限责任公司 2016-08-17 CN disclosed
EP-2751100-B1 METHOD FOR PRODUCING [3-[(6-CHLOR-3-PRIDINYL)METHYL]-2-THIAZOLIDINYLIDENE]CYANAMIDE BAYER IP GMBH (DE) 2015-10-14 EP disclosed
US-20150005502-A1 PROCESS FOR PREPARING [3-[(6-CHLORO-3-PYRIDINYL)METHYL]-2-THIAZOLIDINYLIDENE]CYANAMIDE BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-01-01 US disclosed
EP-2751100-A1 METHOD FOR PRODUCING [3-[(6-CHLOR-3-PRIDINYL)METHYL]-2-THIAZOLIDINYLIDENE]CYANAMIDE Bayer Intellectual Property GmbH (DE) 2014-07-09 EP disclosed
EP-2591673-A1 PEST CONTROL AGENT Meiji Seika Pharma Co., Ltd. (JP) 2013-05-15 EP disclosed
WO-2013030152-A1 METHOD FOR PRODUCING [3-[(6-CHLOR-3-PRIDINYL)METHYL]-2-THIAZOLIDINYLIDENE]CYANAMIDE BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-03-07 WO disclosed
US-RE39140-E1 Heterocyclic compounds BAYER CROPSCIENCE K.K. (JP) 2006-06-20 US disclosed
US-RE39131-E1 Heterocyclic compounds BAYER CROPSCIENCE K.K. (JP) 2006-06-13 US disclosed
US-RE39130-E1 Heterocyclic compounds BAYER CROPSCIENCE K.K. (JP) 2006-06-13 US disclosed
US-5298507-A Insecticides NIHON BAYER AGROCHEM K.K. (JP) 1994-03-29 US disclosed
US-5204360-A Insecticides NIHON BAYER AGROCHEM K.K. (JP) 1993-04-20 US disclosed
JP-H0570431-A NOVEL AMINOALKANETHIOL COMPOUND AND ITS PRODUCTION NIPPON BAYERAGROCHEM KK 1993-03-23 JP disclosed
EP-0235725-B1 HETEROCYCLIC COMPOUNDS NIHON BAYER AGROCHEM K.K. (JP) 1991-11-21 EP disclosed
US-5001138-A Insecticides NIHON TOKUSHU NOYAKU SEIZO, K.K. (JP) 1991-03-19 US disclosed
US-4849432-A INSECTICIDES NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1989-07-18 US disclosed
US-4845106-A INSECTICIDES NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1989-07-04 US disclosed
US-4742060-A 2-(NITROIMINO)- OR 2-(NITROMETHYLENE)-IMIDAZOLIDINES AS INSECTICIDES NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) 1988-05-03 US disclosed
EP-0235725-A2 Heterocyclic compounds NIHON BAYER AGROCHEM K.K. (JP) 1987-09-09 EP disclosed
EP-0192060-A1 Heterocyclic compounds NIHON BAYER AGROCHEM K.K. (JP) 1986-08-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150005502-A1 PROCESS FOR PREPARING [3-[(6-CHLORO-3-PYRIDINYL)METHYL]-2-THIAZOLIDINYLIDENE]CYANAMIDE TPMT, AZI2, TYR KDM4E 659/4885GAA 4420/4885MAPT 1130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.