SCHEMBL1633762

SCHEMBL1633762

OCCNCc1ccc(Cl)nc1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.53
GAA P10253 2/20 0.53
MAPT P10636 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
OXTR P30559 1/20 0.52
AVPR1A P37288 1/20 0.52
CD274 Q9NZQ7 4/20 0.48
PDCD1 Q15116 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.45
ALDH1A1 P00352 2/20 0.45
PLK1 P53350 1/20 0.45
KDM1A O60341 1/20 0.43
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29777000 1.00 KDM4E (0.53) KDM4EGAAMAPTL3MBTL1OXTR
SCHEMBL28412589 0.94 OXTR (0.48) KDM4EGAAMAPTL3MBTL1OXTR
SCHEMBL1798367 0.90 KDM4E (0.50) KDM4EGAAMAPTL3MBTL1OXTR
SCHEMBL9279836 0.85 GAA (0.63) KDM4EGAAMAPTL3MBTL1OXTR
SCHEMBL5833071 0.82 KDM4E (0.53) KDM4EGAAMAPTL3MBTL1OXTR
SCHEMBL5012154 0.82 KDM4E (0.53) KDM4EGAAMAPTL3MBTL1OXTR
SCHEMBL30493949 0.82 KDM4E (0.53) KDM4EGAAMAPTL3MBTL1OXTR
SCHEMBL4854056 0.82 KDM4E (0.53) KDM4EGAAMAPTL3MBTL1OXTR
SCHEMBL1797036 0.82 KDM4E (0.53) KDM4EGAAMAPTL3MBTL1OXTR
SCHEMBL7992427 0.81 GAA (0.60) KDM4EGAAMAPTL3MBTL1OXTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113480541-B Process for producing imidazopyridine compound and intermediate thereof 湖南化工研究院有限公司 2022-09-02 CN claimed
CN-113480541-A Process for producing imidazopyridine compound and intermediate thereof 湖南化工研究院有限公司 2021-10-08 CN claimed
CN-111662283-A Imidazopyridine compound and intermediate, preparation method and application thereof 湖南化工研究院有限公司 2020-09-15 CN claimed
CN-116265461-A Imidazo pyridine thioketone compound, and preparation method and application thereof 湖南化工研究院有限公司 2023-06-20 CN disclosed
EP-2021344-B1 BICYCLIC ENAMINO(THIO)CARBONYL COMPOUNDS BAYER CROPSCIENCE AG (DE) 2013-05-08 EP disclosed
US-7977332-B2 Insecticidal N-(heteroarylalkyl)alkanediamine derivatives FMC CORPORATION (US) 2011-07-12 US disclosed
US-7951951-B2 Bicyclic enamino(thio)carbonyl compounds BAYER CROPSCIENCE AG (DE) 2011-05-31 US disclosed
US-7943642-B2 Insecticidal N,N-di(heteroarylalkyl)amine derivatives FMC CORPORATION (US) 2011-05-17 US disclosed
US-7932393-B2 Insecticidal (heteroarylalky)alkane thio and oxo amine derivatives FMC CORPORATION (US) 2011-04-26 US disclosed
US-20110065710-A1 Insecticidal N-(Heteroarylalkyl)Alkanediamine Derivatives FMC CORPORATION 2011-03-17 US disclosed
US-20100261757-A1 Insecticidal (Heteroarylalky)alkane Thio and Oxo Amine Derivatives FMC CORPORATION 2010-10-14 US disclosed
US-5580889-A Insecticidal nitromethyl or niteoimino-heteromethyl-heterocyclics NIHON BAYER AGROCHEM K.K. (JP) 1996-12-03 US disclosed
US-5461167-A 2-chloro-5-chloromethyl thiazole; insecticide NIHON BAYER AGROCHEM K.K. (JP) 1995-10-24 US disclosed
US-5428032-A Insecticides NIHON BAYER AGROCHEM K.K. (JP) 1995-06-27 US disclosed
US-5298507-A Insecticides NIHON BAYER AGROCHEM K.K. (JP) 1994-03-29 US disclosed
US-5204360-A Insecticides NIHON BAYER AGROCHEM K.K. (JP) 1993-04-20 US disclosed
US-5001138-A Insecticides NIHON TOKUSHU NOYAKU SEIZO, K.K. (JP) 1991-03-19 US disclosed
US-4845106-A INSECTICIDES NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1989-07-04 US disclosed
US-4742060-A 2-(NITROIMINO)- OR 2-(NITROMETHYLENE)-IMIDAZOLIDINES AS INSECTICIDES NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) 1988-05-03 US disclosed
EP-0192060-A1 Heterocyclic compounds NIHON BAYER AGROCHEM K.K. (JP) 1986-08-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110065710-A1 Insecticidal N-(Heteroarylalkyl)Alkanediamine Derivatives DDT, RABL6, ACHE KDM4E 1754/4885GAA 2390/4885MAPT 4362/4885
US-20100261757-A1 Insecticidal (Heteroarylalky)alkane Thio and Oxo Amine Derivatives DDT, AKR7A2, TAAR1 KDM4E 2519/4885GAA 3395/4885MAPT 4608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.