Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | OXTR | P30559 | 1/20 | 0.49 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30493949 | 1.00 | KDM4E (0.53) | KDM4EGAAMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL6444346 | 0.90 | KDM4E (0.60) | KDM4EGAAMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL7761434 | 0.88 | KDM4E (0.65) | KDM4EGAAMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL888411 | 0.85 | KDM4E (0.56) | KDM4EGAAMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL9279836 | 0.85 | GAA (0.63) | KDM4EGAAMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL8372045 | 0.84 | KDM4E (0.51) | KDM4EGAAMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL4854056 | 0.82 | KDM4E (0.53) | KDM4EGAAMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL29777000 | 0.82 | KDM4E (0.53) | KDM4EGAAMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL5833071 | 0.82 | KDM4E (0.53) | KDM4EGAAMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL1797036 | 0.82 | KDM4E (0.53) | KDM4EGAAMAPTL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1884513-A1 | PYRAZOLE COMPOUND AND THERAPEUTIC AGENT FOR DIABETES COMPRISING THE SAME | Japan Tobacco, Inc. (JP) | 2008-02-06 | — | — | EP | claimed |
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | JAPAN TOBACCO INC. (JP) | 2007-02-08 | — | — | US | claimed |
| US-20040152903-A1 | 6-chloro-3-pyridylmethylpropylamine derivatives, preparation process thereof and bactericides | KUREHA CORPORATION (JP) | 2004-08-05 | — | — | US | claimed |
| EP-1375483-A1 | 6-CHLORO-3-PYRIDYLMETHYLPROPYLAMINE DERIVATIVES, PREPARATION PROCESS THEREOF AND BACTERICIDES | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2004-01-02 | — | — | EP | claimed |
| CN-113563322-B | Substituted benzamide isoxazoline derivative or salt acceptable as pesticide, composition and application thereof | 海利尔药业集团股份有限公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-113563322-A | Substituted benzamide isoxazoline derivative or salt and composition thereof acceptable as pesticide and application thereof | 海利尔药业集团股份有限公司 | 2021-10-29 | — | — | CN | disclosed |
| EP-1581546-B1 | AVERMECTIN B1 DERIVATIVES HAVING AN ALKOXYMETHYL SUBSTITUENT IN THE 4''- OR 4'-POSITION | MERIAL INC (US) | 2019-03-20 | — | — | EP | disclosed |
| CN-104119268-A | Preparation and application of trifluoroacetyl anabasine compounds with insecticidal activity | UNIV JINAN | 2014-10-29 | — | — | CN | disclosed |
| US-8263566-B2 | Avermectin B1 and avermectin B1 monosaccharide derivatives having an alkoxymethyl substituent in the 4″-or 4′-position | MERIAL LIMITED (US) | 2012-09-11 | — | — | US | disclosed |
| US-20110230429-A1 | AVERMECTIN B1 AND AVERMECTIN B1 MONOSACCHARIDE DERIVATIVES HAVING AN ALKOXYMETHYL SUBSTITUENT IN THE 4\"-OR 4'-POSITION | SYNGENTA CROP PROTECTION, LLC (US) | 2011-09-22 | — | — | US | disclosed |
| US-8017589-B2 | Avermectin B1 and avermectin B1 monosaccharide derivatives having an alkoxymethyl substituent in the 4″-or 4′-position | SYNGENTA CROP PROTECTION LLC (US) | 2011-09-13 | — | — | US | disclosed |
| US-8017589-B2 | Avermectin B1 and avermectin B1 monosaccharide derivatives having an alkoxymethyl substituent in the 4″-or 4′-position | SYNGENTA CROP PROTECTION LLC (US) | 2011-09-13 | — | — | US | disclosed |
| CN-1091737-A | The method for preparing amine compound or its salt | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-09-07 | — | — | CN | disclosed |
| EP-0302389-B1 | Alpha-unsaturated amines, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-5214152-A | Insecticides, miticides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-05-25 | — | — | US | disclosed |
| EP-0529680-A2 | Intermediates, their production and their use for preparing alpha-unsaturated amines | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-5175301-A | Insecticide, miticide, pesticide | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-12-29 | — | — | US | disclosed |
| EP-0509559-A2 | Alpha-unsaturated amines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-10-21 | — | — | EP | disclosed |
| CN-1031079-A | Alpha-unsaturated amines, process for their production and their use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1989-02-15 | — | — | CN | disclosed |
| EP-0302389-A2 | Alpha-unsaturated amines, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-02-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | PYGL, GYS2, AGL | KDM4E 3446/4885GAA 53/4885MAPT 4621/4885 |
| US-20040152903-A1 | 6-chloro-3-pyridylmethylpropylamine derivatives, preparation process thereof and bactericides | PGLS, TLR6, UROD | KDM4E 330/4885GAA 3031/4885MAPT 3934/4885 |
| US-20110230429-A1 | AVERMECTIN B1 AND AVERMECTIN B1 MONOSACCHARIDE DERIVATIVES HAVING AN ALKOXYMETHYL SUBSTITUENT IN THE 4\"-OR 4'-POSITION | CHRM1, CHRM2, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | KDM4E 2892/4885GAA 4535/4885MAPT 1693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.