Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | OXTR | P30559 | 1/20 | 0.49 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | MC5R | P33032 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5884859 | 0.97 | KDM4E (0.50) | KDM4EGAAMAPTL3MBTL1OXTR | |
| SCHEMBL7992477 | 0.93 | KDM4E (0.50) | KDM4EGAAMAPTL3MBTL1OXTR | |
| SCHEMBL10483911 | 0.92 | KDM4E (0.49) | KDM4EGAAMAPTL3MBTL1OXTR | |
| Hydrochloric Acid SCHEMBL7504260 | 0.92 | OXTR (0.49) | KDM4EGAAMAPTL3MBTL1OXTR | |
| SCHEMBL501967 | 0.86 | KDM4E (0.50) | KDM4EGAAMAPTL3MBTL1OXTR | |
| SCHEMBL1797036 | 0.86 | KDM4E (0.53) | KDM4EGAAMAPTL3MBTL1OXTR | |
| SCHEMBL9279836 | 0.85 | GAA (0.63) | KDM4EGAAMAPTL3MBTL1OXTR | |
| SCHEMBL10483901 | 0.84 | SIGMAR1 (0.56) | KDM4EGAAMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL1798367 | 0.83 | KDM4E (0.50) | KDM4EGAAMAPTL3MBTL1OXTR | |
| SCHEMBL6444346 | 0.83 | KDM4E (0.60) | KDM4EGAAMAPTL3MBTL1OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0474057-B1 | Process for the preparation of N-(2-chloro-pyridine-5-yl-methyl)-ethylendiamin | BAYER AG (DE) | 1995-11-08 | — | — | EP | claimed |
| EP-0542086-B1 | Process for the preparation of the N-[(2-chloropyridin-5-yl)methyl]-ethylenediamine | BAYER AG (DE) | 1994-11-02 | — | — | EP | claimed |
| US-5352794-A | Process for the preparation of N-(2-chloro-pyridin-5-yl-methyl)ethylenediamine | BAYER AKTIENGESELLSCHAFT (DE) | 1994-10-04 | — | — | US | claimed |
| EP-0542086-A1 | Process for the preparation of the N-[(2-chloropyridin-5-yl)methyl]-ethylenediamine | BAYER AG (DE) | 1993-05-19 | — | — | EP | claimed |
| US-5164508-A | PROCESS FOR THE PREPARATION OF N-(2-CHLORO-PYRIDIN-5-YL-METHYL)-ETHYLENEDIAMINE | BAYER AKTIENGESELLSCHAFT (DE) | 1992-11-17 | — | — | US | claimed |
| EP-0474057-A1 | Process for the preparation of N-(2-chloro-pyridine-5-yl-methyl)-ethylendiamin | BAYER AG (DE) | 1992-03-11 | — | — | EP | claimed |
| US-4767864-A | Process for the preparation of nitromethylene derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1988-08-30 | — | — | US | claimed |
| JP-4217957-A | — | — | None | — | — | JP | disclosed |
| JP-7242633-A | — | — | None | — | — | JP | disclosed |
| US-20190150445-A1 | SUBSTITUTED HALOGEN(THIO)ACYL COMPOUNDS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-05-23 | — | — | US | disclosed |
| EP-2984930-B1 | PEST CONTROL AGENT | MEIJI SEIKA PHARMA CO LTD (JP) | 2018-10-03 | — | — | EP | disclosed |
| US-10085449-B2 | N-[1-((6-chloropyridin-3-yl)methyl)pyridin-2(1H)-ylidene]-2,2,2- trifluoroacetamide for control of agricultural/horticultural pests | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2018-10-02 | — | — | US | disclosed |
| US-20180042233-A1 | NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE HAVING 2-IMINO GROUP AND PEST CONTROL AGENT INCLUDING THE SAME | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2018-02-15 | — | — | US | disclosed |
| EP-0268915-A2 | Trifluoromethylcarbonyl derivatives | BAYER AG (DE) | 1988-06-01 | — | — | EP | disclosed |
| US-4742060-A | 2-(NITROIMINO)- OR 2-(NITROMETHYLENE)-IMIDAZOLIDINES AS INSECTICIDES | NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) | 1988-05-03 | — | — | US | disclosed |
| EP-0254859-A2 | Alkylene diamines | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1988-02-03 | — | — | EP | disclosed |
| EP-0235725-A2 | Heterocyclic compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1987-09-09 | — | — | EP | disclosed |
| US-4678795-A | 1-pyridylmethyl-2-nitromethylene-1,3-diazacycloalkane insecticides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1987-07-07 | — | — | US | disclosed |
| EP-0192060-A1 | Heterocyclic compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1986-08-27 | — | — | EP | disclosed |
| EP-0163855-A1 | Nitromethylene derivatives, intermediates, and process for their preparation as insecticides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1985-12-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180042233-A1 | NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE HAVING 2-IMINO GROUP AND PEST CONTROL AGENT INCLUDING THE SAME | CBR1, CBR3, NIT2 | KDM4E 1283/4885GAA 4671/4885MAPT 4773/4885 |
| US-10085449-B2 | N-[1-((6-chloropyridin-3-yl)methyl)pyridin-2(1H)-ylidene]-2,2,2- trifluoroacetamide for control of agricultural/horticultural pests | NR2E1, CROCC, PRMT1 | KDM4E 95/4885GAA 4426/4885MAPT 3396/4885 |
| US-20190150445-A1 | SUBSTITUTED HALOGEN(THIO)ACYL COMPOUNDS | ACOT7, AGPAT5, TST | KDM4E 2332/4885GAA 2591/4885MAPT 4359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.