SCHEMBL5833111

SCHEMBL5833111

N[C@@H](Cc1ccc(O)c(C=O)c1)C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 5/20 0.69
USP2 O75604 3/20 0.69
PTGS1 P23219 2/20 0.69
KDM4E B2RXH2 2/20 0.69
ALOX15 P16050 2/20 0.69
RECQL P46063 2/20 0.69
HIF1A Q16665 2/20 0.69
HSD17B10 Q99714 2/20 0.69
TDP1 Q9NUW8 2/20 0.69
EGFR P00533 1/20 0.69
LCK P06239 1/20 0.69
FYN P06241 1/20 0.69
ADORA3 P0DMS8 1/20 0.69
HTR2A P28223 1/20 0.69
PTGS2 P35354 1/20 0.69
CDK1 P06493 1/20 0.53
PKM P14618 3/20 0.51
ALPI P09923 1/20 0.50
XIAP P98170 1/20 0.50
GRIA2 P42262 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11674803 1.00 SLC7A5 (0.69) SLC7A5USP2PTGS1KDM4EALOX15
SCHEMBL29733305 1.00 SLC7A5 (0.69) SLC7A5USP2PTGS1KDM4EALOX15
Hydrochloric Acid SCHEMBL11673446 0.98 SLC7A5 (0.67) SLC7A5USP2PTGS1KDM4EALOX15
Threonine SCHEMBL17438165 0.89 SLC7A5 (0.56) SLC7A5USP2PTGS1KDM4EALOX15
SCHEMBL22057183 0.83 CDK1 (0.51) SLC7A5USP2PTGS1KDM4EALOX15
Levodopa SCHEMBL28209611 0.83 SLC7A5 (0.87) SLC7A5USP2PTGS1KDM4EALOX15
SCHEMBL17202759 0.82 SLC7A5 (0.53) SLC7A5USP2PTGS1KDM4EALOX15
SCHEMBL17202762 0.82 SLC7A5 (0.53) SLC7A5USP2PTGS1KDM4EALOX15
Levodopa SCHEMBL11000382 0.82 SLC7A5 (1.00) SLC7A5USP2PTGS1KDM4EALOX15
Levodopa SCHEMBL116907 0.82 SLC7A5 (1.00) SLC7A5USP2PTGS1KDM4EALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117642185-A Improved CD30 targeting antibody drug conjugates and uses thereof 路德维希-马克西米利安慕尼黑大学 2024-03-01 CN claimed
EP-4267193-A1 IMPROVED CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF Ludwig-Maximilians-Universität München (DE) 2023-11-01 EP claimed
WO-2022136555-A9 IMPROVED CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) 2022-09-22 WO claimed
WO-2022136555-A1 IMPROVED CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) 2022-06-30 WO claimed
US-20220193251-A1 CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) 2022-06-23 US claimed
US-10208084-B2 Means and methods for site-specific functionalization of polypeptides LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) 2019-02-19 US claimed
US-20170349625-A1 MEANS AND METHODS FOR SITE-SPECIFIC FUNCTIONALIZATION OF POLYPEPTIDES FORSCHUNGSVERBUND BERLIN E.V. (DE) 2017-12-07 US claimed
EP-3212659-A1 MEANS AND METHODS FOR SITE-SPECIFIC FUNCTIONALIZATION OF POLYPEPTIDES Ludwig-Maximilians-Universität München (DE) 2017-09-06 EP claimed
WO-2016066749-A1 MEANS AND METHODS FOR SITE-SPECIFIC FUNCTIONALIZATION OF POLYPEPTIDES LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) 2016-05-06 WO claimed
EP-0483261-A1 HIRUDIN PEPTIDE DERIVATIVES BIOGEN, INC. (US) 1992-05-06 EP claimed
WO-1991001328-A1 HIRUDIN PEPTIDE DERIVATIVES BIOGEN, INC. (US) 1991-02-07 WO claimed
EP-3688007-B1 BIOCONJUGATION OF POLYPEPTIDES UNIV YORK (GB) 2024-07-31 EP disclosed
US-11958880-B2 Means and methods for site-specific functionalization of polypeptides LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) 2024-04-16 US disclosed
CN-117642185-A Improved CD30 targeting antibody drug conjugates and uses thereof 路德维希-马克西米利安慕尼黑大学 2024-03-01 CN disclosed
US-11897917-B2 Bioconjugation of polypeptides THE UNIVERSITY OF YORK (GB) 2024-02-13 US disclosed
EP-0482069-A1 COMBINATIONS AND METHODS FOR TREATING OR PREVENTING THROMBOTIC DISEASES BIOGEN, INC. (US) 1992-04-29 EP disclosed
WO-1991002750-A1 NOVEL INHIBITORS OF THROMBIN BIOGEN, INC. (US) 1991-03-07 WO disclosed
WO-1991001328-A1 HIRUDIN PEPTIDE DERIVATIVES BIOGEN, INC. (US) 1991-02-07 WO disclosed
WO-1991001142-A1 COMBINATIONS AND METHODS FOR TREATING OR PREVENTING THROMBOTIC DISEASES BIOGEN, INC. (US) 1991-02-07 WO disclosed
US-4022910-A L-3-hydroxymethyltyrosine and salts thereof for lowering blood pressure RICHARDSON-MERRELL INC. (US) 1977-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170349625-A1 MEANS AND METHODS FOR SITE-SPECIFIC FUNCTIONALIZATION OF POLYPEPTIDES PTMS, DNPEP, LNPEP SLC7A5 674/4885USP2 1380/4885PTGS1 4863/4885
US-11897917-B2 Bioconjugation of polypeptides PTMS, EPCAM, IAPP SLC7A5 3151/4885USP2 2547/4885PTGS1 3948/4885
US-10208084-B2 Means and methods for site-specific functionalization of polypeptides PTMS, DNPEP, LNPEP SLC7A5 674/4885USP2 1380/4885PTGS1 4863/4885
US-11958880-B2 Means and methods for site-specific functionalization of polypeptides PTMS, DNPEP, LNPEP SLC7A5 674/4885USP2 1380/4885PTGS1 4863/4885
US-20220193251-A1 CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF TUBB6, GALNT10, TUBB SLC7A5 451/4885USP2 3052/4885PTGS1 4867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.