Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 4/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 2/20 | 0.41 |
| ▸ | ALPI | P09923 | 2/20 | 0.41 |
| ▸ | ALPG | P10696 | 2/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 4/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29403669 | 0.82 | LCK (0.64) | LCKTRPA1KDM4ERAB9APTGS2 | |
| SCHEMBL170797 | 0.82 | LCK (0.64) | LCKTRPA1KDM4ERAB9APTGS2 | |
| Formic Acid SCHEMBL29030387 | 0.75 | KDM4E (0.61) | LCKTRPA1KDM4ERAB9APTGS2 | |
| Ethylene Glycol SCHEMBL3050436 | 0.75 | LCK (0.54) | LCKTRPA1KDM4ERAB9APTGS2 | |
| SCHEMBL22531380 | 0.74 | TRPA1 (0.42) | LCKTRPA1KDM4ERAB9APTGS2 | |
| Sulfuric Acid SCHEMBL23249872 | 0.73 | KDM4E (0.54) | LCKTRPA1KDM4ERAB9APTGS2 | |
| Styrene SCHEMBL4416848 | 0.73 | ALDH1A1 (0.58) | LCKTRPA1KDM4ERAB9APTGS2 | |
| Acetone SCHEMBL22719872 | 0.73 | IAPP (0.58) | LCKTRPA1KDM4ERAB9APTGS2 | |
| Acetic Acid SCHEMBL29030379 | 0.72 | IAPP (0.56) | LCKTRPA1KDM4ERAB9APTGS2 | |
| SCHEMBL29681431 | 0.71 | EGFR (0.56) | LCKKDM4ERAB9APTGS2BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7109329-B2 | Neurologically active compounds and compounds with multiple activities | NAFTCHI N ERIC | 2006-09-19 | — | — | US | claimed |