Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5834336 | 0.91 | MET (0.31) | BTK | |
| SCHEMBL5833671 | 0.81 | MAOA (0.51) | BTKMAOA | |
| SCHEMBL6765855 | 0.77 | TRPV1 (0.30) | BTKMAOA | |
| SCHEMBL5833681 | 0.75 | BTK (0.36) | BTK | |
| SCHEMBL12665398 | 0.75 | GRM2 (0.35) | MAOA | |
| SCHEMBL7081127 | 0.74 | MAOA (0.34) | MAOA | |
| SCHEMBL7081128 | 0.74 | MAOA (0.34) | MAOA | |
| SCHEMBL5834330 | 0.74 | MAOA (0.48) | MAOA | |
| Posizolid SCHEMBL374786 | 0.73 | MAOA (0.34) | BTKMAOA | |
| Posizolid SCHEMBL7079325 | 0.73 | MAOA (0.34) | BTKMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7087629-B2 | Useful activity against Gram-positive pathogens and, in particular, against various strains exhibiting resistance to vancomycin and against E. faecium strains resistant to both aminoglycosides and clinically used beta-lactams | ASTRAZENECA AB (SE) | 2006-08-08 | — | — | US | disclosed |
| US-6734200-B1 | ANTIBIOTIC COMPOUNDS CONTAINING A SUBSTITUTED OXAZOLIDINONE RING; ACTIVITY AGAINST GRAM-POSITIVE PATHOGENS | ASTRAZENECA AB (SE) | 2004-05-11 | — | — | US | disclosed |