Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5834337 | 0.91 | LNPEP (0.31) | BTK | |
| SCHEMBL5833675 | 0.75 | BTK (0.36) | BTK | |
| SCHEMBL5833671 | 0.75 | MAOA (0.51) | BTK | |
| SCHEMBL7081128 | 0.69 | MAOA (0.34) | — | |
| SCHEMBL7081127 | 0.69 | MAOA (0.34) | — | |
| SCHEMBL12665398 | 0.68 | GRM2 (0.35) | — | |
| SCHEMBL5834336 | 0.67 | MET (0.31) | BTK | |
| SCHEMBL5834248 | 0.67 | MAOA (0.49) | — | |
| SCHEMBL5834330 | 0.67 | MAOA (0.48) | — | |
| SCHEMBL7077036 | 0.67 | MAOA (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7087629-B2 | Useful activity against Gram-positive pathogens and, in particular, against various strains exhibiting resistance to vancomycin and against E. faecium strains resistant to both aminoglycosides and clinically used beta-lactams | ASTRAZENECA AB (SE) | 2006-08-08 | — | — | US | disclosed |
| US-6734200-B1 | ANTIBIOTIC COMPOUNDS CONTAINING A SUBSTITUTED OXAZOLIDINONE RING; ACTIVITY AGAINST GRAM-POSITIVE PATHOGENS | ASTRAZENECA AB (SE) | 2004-05-11 | — | — | US | disclosed |