SCHEMBL5833719

SCHEMBL5833719

C=C(C)C(=O)Nc1nc(N)nc(N)n1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.43
RXFP1 Q9HBX9 1/20 0.37
TDP1 Q9NUW8 2/20 0.36
ALDH1A1 P00352 3/20 0.33
POLB P06746 3/20 0.33
BAZ1A Q9NRL2 1/20 0.33
HPGD P15428 2/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
NLRP1 Q9C000 1/20 0.33
CYP1A2 P05177 3/20 0.32
GAA P10253 2/20 0.32
RECQL P46063 2/20 0.32
BLM P54132 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
ATM Q13315 1/20 0.32
KDM4E B2RXH2 2/20 0.32
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4461476 0.85 RXFP1 (0.42) LMNARXFP1TDP1ALDH1A1POLB
SCHEMBL21303921 0.85 LMNA (0.32) LMNARXFP1TDP1
SCHEMBL3298153 0.79 POLB (0.52) LMNAALDH1A1POLBCYP1A2GAA
SCHEMBL24313998 0.78 RXFP1 (0.38) LMNARXFP1TDP1ALDH1A1POLB
SCHEMBL5052723 0.77 CYP1A2 (0.40) CYP1A2
SCHEMBL13554533 0.74 POLB (0.52) LMNAALDH1A1POLBHPGDCYP1A2
Methacrylic Acid SCHEMBL195249 0.73 LMNA (0.54) LMNATDP1ALDH1A1POLBHPGD
SCHEMBL5916292 0.73 TDP1 (0.63) LMNATDP1ALDH1A1HPGDCYP1A2
Methacrylic Acid SCHEMBL23358775 0.73 LMNA (0.54) LMNATDP1ALDH1A1POLBHPGD
SCHEMBL21303918 0.73 RXFP1 (0.35) LMNARXFP1TDP1ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180105618-A1 N-HALAMINE MELAMINE DERIVATIVES AS NOVEL DECONTAMINATION AND BIOCIDAL AGENTS STATE OF ISRAEL PRIME MINISTER'S OFFICE ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH (IL) 2018-04-19 US disclosed
US-20180105618-A1 N-HALAMINE MELAMINE DERIVATIVES AS NOVEL DECONTAMINATION AND BIOCIDAL AGENTS STATE OF ISRAEL PRIME MINISTER'S OFFICE ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH (IL) 2018-04-19 US disclosed
US-7024084-B2 Electrodeposition solution, optical part produced therefrom, and production method for same optical part FUJI XEROX CO., LTD. (JP) 2006-04-04 US disclosed
US-6797531-B2 Process for producing microlens array, array master, electrolytic solution and microlens array resin material therefor and apparatus for producing master FUJI XEROX CO., LTD. (JP) 2004-09-28 US disclosed
US-20040057688-A1 Electrodeposition solution, optical part produced therefrom, and production method for same optical part FUJI XEROX CO., LTD. (JP) 2004-03-25 US disclosed
US-6707612-B2 RADIATING WITH LIGHT REGION OF PHOTO-SEMICONDUCTOR THIN FILM TO APPLY VOLTAGE BETWEEN COUNTERELECTRODE; PRECIPITATION FUJI XEROX CO., LTD. (JP) 2004-03-16 US disclosed
US-20040001259-A1 Process for producing microlens array, array master, electrolytic solution and microlens array resin material therefor and apparatus for producing master FUJI XEROX CO., LTD. (JP) 2004-01-01 US disclosed
US-20030142409-A1 Method of manufacturing micro-lens array, electrolyte and manufacturing apparatus used therefor FUJI XEROX CO., LTD. (JP) 2003-07-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180105618-A1 N-HALAMINE MELAMINE DERIVATIVES AS NOVEL DECONTAMINATION AND BIOCIDAL AGENTS HNMT, CAT, TYR LMNA 1687/4885RXFP1 4750/4885TDP1 2172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.