SCHEMBL4461476

SCHEMBL4461476

C=C(C)C(=O)Nc1nc(NC(=O)C(=C)C)nc(NC(=O)C(=C)C)n1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.42
TDP1 Q9NUW8 2/20 0.41
POLB P06746 4/20 0.39
ALDH1A1 P00352 4/20 0.38
BAZ1A Q9NRL2 1/20 0.37
LMNA P02545 1/20 0.37
HPGD P15428 1/20 0.37
HTT P42858 1/20 0.37
KMT2A Q03164 1/20 0.37
NLRP1 Q9C000 1/20 0.37
CYP1A2 P05177 2/20 0.36
KDM4E B2RXH2 1/20 0.36
RECQL P46063 2/20 0.36
BLM P54132 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.35
ADORA3 P0DMS8 2/20 0.33
TGFBR1 P36897 1/20 0.33
ADORA1 P30542 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24313998 0.91 RXFP1 (0.38) RXFP1TDP1POLBALDH1A1BAZ1A
SCHEMBL21303918 0.86 RXFP1 (0.35) RXFP1TDP1POLBALDH1A1BAZ1A
SCHEMBL5833719 0.85 LMNA (0.43) RXFP1TDP1POLBALDH1A1BAZ1A
SCHEMBL8079170 0.78 HTT (0.55) RXFP1TDP1ALDH1A1LMNAHPGD
SCHEMBL21303921 0.75 LMNA (0.32) RXFP1TDP1LMNA
SCHEMBL3299561 0.73 POLB (0.62) POLBALDH1A1HPGDCYP1A2KDM4E
Sulfuric Acid SCHEMBL5242033 0.72 HTT (0.49) RXFP1TDP1POLBALDH1A1LMNA
SCHEMBL10148817 0.72 TDP1 (0.51) RXFP1TDP1POLBALDH1A1LMNA
SCHEMBL439393 0.70 RXFP1 (0.74) RXFP1TDP1POLBALDH1A1BAZ1A
SCHEMBL24491092 0.68 GRM1 (0.43) RXFP1TDP1POLBALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070265365-A1 Water Soluble Polymers Containing Vinyl Unsaturation, Their Crosslinking and Process for Preparation Thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2007-11-15 US claimed
US-20060094844-A1 Inclusion complexes of unsaturated monomers, their polymers and process for preparation thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH 2006-05-04 US claimed
US-7560522-B2 Inclusion complexes of unsaturated monomers, their polymers and process for preparation thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2009-07-14 US disclosed
US-20070213486-A1 Inclusion complexes of unsaturated monomers, their polymers and process for preparation thereof PATIL PRERANA M 2007-09-13 US disclosed
US-20070213489-A1 Inclusion complexes of unsaturated monomers, their polymers and process for preparation thereof PATIL PRERANA M 2007-09-13 US disclosed
US-20070213470-A1 Inclusion complexes of unsaturated monomers, their polymers and process for preparation thereof PATIL PRERANA M 2007-09-13 US disclosed
US-20060094844-A1 Inclusion complexes of unsaturated monomers, their polymers and process for preparation thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH 2006-05-04 US disclosed