Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5834074 | 0.82 | CYP2E1 (0.35) | MAOA | |
| SCHEMBL6765855 | 0.77 | TRPV1 (0.30) | MAOA | |
| SCHEMBL6765854 | 0.60 | CYP2E1 (0.35) | MAOA | |
| SCHEMBL7134192 | 0.57 | MAOB (0.48) | MAOA | |
| SCHEMBL7084774 | 0.57 | MAOB (0.48) | MAOA | |
| SCHEMBL5767289 | 0.56 | MAOA (0.48) | MAOA | |
| SCHEMBL3042429 | 0.56 | MAOA (0.48) | MAOA | |
| SCHEMBL14274374 | 0.54 | CALML3 (0.67) | MAOA | |
| SCHEMBL6233210 | 0.53 | MAOA (0.45) | MAOA | |
| SCHEMBL27573655 | 0.53 | MAOA (0.45) | MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7087629-B2 | Useful activity against Gram-positive pathogens and, in particular, against various strains exhibiting resistance to vancomycin and against E. faecium strains resistant to both aminoglycosides and clinically used beta-lactams | ASTRAZENECA AB (SE) | 2006-08-08 | — | — | US | disclosed |