SCHEMBL5834207

SCHEMBL5834207

C=CCCC(C)[SiH](OCCCC)OCCCC

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.41
ALDH1A1 P00352 1/20 0.41
PLA2G2C Q5R387 1/20 0.36
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2244298 0.91 TSHR (0.45) TSHRALDH1A1PLA2G2CHPGD
SCHEMBL5833484 0.89 TSHR (0.37) TSHRALDH1A1PLA2G2C
SCHEMBL5833766 0.82 ADRB2 (0.33) TSHR
SCHEMBL2244285 0.81 TSHR (0.41) TSHRALDH1A1PLA2G2C
SCHEMBL5834008 0.80 TSHR (0.35) TSHRALDH1A1
SCHEMBL28898369 0.76 OPRM1 (0.34) PLA2G2C
SCHEMBL2772303 0.76 ADRB2 (0.35) TSHRALDH1A1
SCHEMBL17937860 0.76
SCHEMBL2861941 0.76 CYP3A4 (0.37) TSHRALDH1A1
SCHEMBL17937705 0.76 TSHR (0.37) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7005532-B2 Process of producing alkoxysilanes TOAGOSEI CO., LTD. (JP) 2006-02-28 US disclosed
US-20050020845-A1 Process of producing alkoxysilanes TOAGOSEI CO., LTD. (JP) 2005-01-27 US disclosed
EP-1428828-A1 PROCESS FOR PREPARATION OF ALKOXYSILANES TOAGOSEI CO., LTD. (JP) 2004-06-16 EP disclosed