SCHEMBL2244285

SCHEMBL2244285

C=CCCCC(C)[SiH](OCCC)OCCC

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
ALDH1A1 P00352 1/20 0.41
PLA2G2C Q5R387 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2244298 0.91 TSHR (0.45) TSHRALDH1A1PLA2G2C
SCHEMBL5833484 0.89 TSHR (0.37) TSHRALDH1A1PLA2G2C
SCHEMBL2240914 0.85 TSHR (0.39) TSHRALDH1A1
SCHEMBL3481696 0.82 DNM1 (0.32)
SCHEMBL5834207 0.81 TSHR (0.41) TSHRALDH1A1PLA2G2C
SCHEMBL28079113 0.80 OPRM1 (0.39)
SCHEMBL6427177 0.79
SCHEMBL29126580 0.79 OPRM1 (0.38) TSHR
SCHEMBL6303527 0.79 OPRM1 (0.38) TSHR
SCHEMBL28078988 0.79 OPRM1 (0.38) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7994250-B2 Vinyl-urethane copolymers with intermediary linkage segments having silicon-oxygen bonds and production methods thereof KONISHI CO., LTD. (JP) 2011-08-09 US disclosed
US-20090326151-A1 HAIR COSMETIC KONISHI CO., LTD. (JP) 2009-12-31 US disclosed
EP-2039347-A1 COSMETIC HAIR PREPARATION Shiseido Company, Limited (JP) 2009-03-25 EP disclosed
EP-1837360-A1 VINYL-URETHANE COPOLYMER AND METHOD FOR PRODUCING SAME Konishi Co., Ltd. (JP) 2007-09-26 EP disclosed
US-20070117902-A1 Vinyl-urethane copolymers and production methods thereof KONISHI CO., LTD. (JP) 2007-05-24 US disclosed