Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | ABCC1 | P33527 | 4/20 | 0.67 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | NPY1R | P25929 | 1/20 | 0.54 |
| ▸ | MC4R | P32245 | 1/20 | 0.54 |
| ▸ | NPY2R | P49146 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5834575 | 0.86 | ABCB1 (0.67) | ALDH1A1ABCC1ABCB1HDAC1HDAC2 | |
| SCHEMBL1455286 | 0.79 | KMT2A (0.90) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL13401489 | 0.79 | ALDH1A1 (0.72) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL1454743 | 0.77 | MAPT (0.70) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL5724398 | 0.77 | HDAC1 (1.00) | HDAC1HDAC2KDM4EKCNMA1 | |
| SCHEMBL9491267 | 0.77 | CXCR2 (0.70) | ALDH1A1MAPTABCC1ABCB1MEN1 | |
| SCHEMBL6748184 | 0.76 | CXCR2 (0.58) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL3619864 | 0.76 | MAPT (0.61) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL1897629 | 0.75 | CRHBP (0.58) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL8026664 | 0.75 | MAPT (0.67) | ALDH1A1MAPTMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7138425-B2 | Phthalimide carboxylic acid derivatives | OXFORD GLYCOSCIENCE (UK) LTD. (GB) | 2006-11-21 | — | — | US | disclosed |
| US-20050203153-A1 | Phthalimide carboxylic acid derivatives | OXFORD GLYCOSCIENCE (UK) LTD. (GB) | 2005-09-15 | — | — | US | disclosed |
| EP-1483261-A1 | PHTHALIMIDE CARBOXYLIC ACID DERIVATIVES | Oxford GlycoSciences (UK) Ltd, Attn: Mary Gadsden (GB) | 2004-12-08 | — | — | EP | disclosed |
| WO-2003074516-A1 | PHTHALIMIDE CARBOXYLIC ACID DERIVATIVES | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2003-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203153-A1 | Phthalimide carboxylic acid derivatives | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HCCS, IDH1 | ALDH1A1 160/4885MAPT 1342/4885ABCC1 1160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.