Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.58 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.58 |
| ▸ | VCAM1 | P19320 | 9/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | DHFR | P00374 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2461199 | 0.92 | VCAM1 (0.58) | VCAM1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5992360 | 0.90 | VCAM1 (0.60) | VCAM1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9251355 | 0.85 | TSHR (0.58) | CRHBPCRHR2VCAM1MAPTMEN1 | |
| SCHEMBL1901253 | 0.84 | VCAM1 (0.53) | VCAM1MAPTMEN1KMT2ALMNA | |
| SCHEMBL9808910 | 0.82 | MAPT (0.48) | CRHBPCRHR2VCAM1MAPTMEN1 | |
| SCHEMBL1663325 | 0.82 | CRHBP (0.63) | CRHBPCRHR2MAPTMEN1KMT2A | |
| SCHEMBL10663504 | 0.82 | MAPT (0.66) | VCAM1MAPTMEN1KMT2ALMNA | |
| SCHEMBL14956482 | 0.82 | VCAM1 (0.60) | VCAM1ALDH1A1 | |
| SCHEMBL11672825 | 0.81 | CRHBP (0.67) | CRHBPCRHR2VCAM1MAPTMEN1 | |
| SCHEMBL2816974 | 0.81 | CRHBP (0.61) | CRHBPCRHR2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11588110-B2 | Heterocyclic compound and organic light emitting device comprising the same | LT MATERIALS CO., LTD. (KR) | 2023-02-21 | — | — | US | disclosed |
| US-20200373499-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME | LT MATERIALS CO., LTD. (KR) | 2020-11-26 | — | — | US | disclosed |
| CN-101767018-B | Loading type Pd base metal nanometer cluster catalyst, preparing method and applications thereof | UNIV BEIJING | 2012-06-13 | — | — | CN | disclosed |
| US-7947191-B2 | Composite material composed of nanoparticles of transition metal and magnetic ferric oxide, a methode of preparing the same, and uses of the same | PEIKING UNIVERSITY (CN) | 2011-05-24 | — | — | US | disclosed |
| CN-101767018-A | Loading type Pd base metal nanometer cluster catalyst, preparing method and applications thereof | UNIV BEIJING | 2010-07-07 | — | — | CN | disclosed |
| US-7671195-B2 | Process for preparing dibenzothiazepine compounds | ASTRAZENECA UK LIMITED (GB) | 2010-03-02 | — | — | US | disclosed |
| CN-100494076-C | Transition metal-magnetic ferric oxide nano-composite material, its production and uses | UNIV BEIJING (CN) | 2009-06-03 | — | — | CN | disclosed |
| US-20090124834-A1 | COMPOSITE MATERIAL COMPOSED OF NANOPARTICLES OF TRANSITION METAL AND MAGNETIC FERRIC OXIDE, A METHODE OF PREPARING THE SAME, AND USES OF THE SAME | PEIKING UNIVERSITY (KR) | 2009-05-14 | — | — | US | disclosed |
| EP-1996568-A2 | PROCESS FOR PREPARING DIBENZOTHIAZEPINE COMPOUNDS | AstraZeneca UK Limited (GB) | 2008-12-03 | — | — | EP | disclosed |
| US-7368462-B1 | Melanin concentrating hormone antagonists | THE PROCTER & GAMBLE COMPANY (US) | 2008-05-06 | — | — | US | disclosed |
| US-20060173178-A1 | Process for preparing dibenzothiazepine derivatives | UBE INDUSTRIES, LTD. (JP) | 2006-08-03 | — | — | US | disclosed |
| US-7045621-B1 | Process for producing dibenzothiazepine derivatives | UBE INDUSTRIES, LTD. (JP) | 2006-05-16 | — | — | US | disclosed |
| EP-1201663-A1 | PROCESS FOR PRODUCING DIBENZOTHIAZEPINE DERIVATIVES | Ube Industries, Ltd. (JP) | 2002-05-02 | — | — | EP | disclosed |
| EP-0268849-B1 | Poly(aminoaromatic) compounds | DOW CHEMICAL CO (US) | 1993-10-20 | — | — | EP | disclosed |
| US-5079275-A | Polyamino compound is an amino endcapped polyether, polyester, polycarbonate, resole, hydroxybutadiene | THE DOW CHEMICAL COMPANY (US) | 1992-01-07 | — | — | US | disclosed |
| US-4847416-A | Capping of polyols with aromatic amines | THE DOW CHEMICAL COMPANY (US) | 1989-07-11 | — | — | US | disclosed |
| EP-0268849-A2 | Poly(aminoaromatic) compounds | THE DOW CHEMICAL COMPANY (US) | 1988-06-01 | — | — | EP | disclosed |
| US-4670566-A | ANTIIFLAMMATORY AGENTS, ANTICOAGULANTS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1987-06-02 | — | — | US | disclosed |
| US-4259475-A | FRIEDEL-CRAFTS COMPLEX CATALYST | EXXON RESEARCH & ENGINEERING CO. (US) | 1981-03-31 | — | — | US | disclosed |
| US-4059627-A | HYDROGENATION OF CHLORINATED NITRO AROMATIC, NOBLE METAL CATALYST, THIOETHER | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060173178-A1 | Process for preparing dibenzothiazepine derivatives | TPMT, BBOX1, NISCH | CRHBP 2069/4885CRHR2 3354/4885VCAM1 2305/4885 |
| US-20090124834-A1 | COMPOSITE MATERIAL COMPOSED OF NANOPARTICLES OF TRANSITION METAL AND MAGNETIC FERRIC OXIDE, A METHODE OF PREPARING THE SAME, AND USES OF THE SAME | FECH, FTO, HMOX1 | CRHBP 3273/4885CRHR2 3673/4885VCAM1 3850/4885 |
| US-11588110-B2 | Heterocyclic compound and organic light emitting device comprising the same | CRY1, CYP1A1, CYP1B1 | CRHBP 4047/4885CRHR2 3049/4885VCAM1 3441/4885 |
| US-20200373499-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME | CRY1, CYP1A1, CYP1B1 | CRHBP 4047/4885CRHR2 3049/4885VCAM1 3441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.