Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 8/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16166363 | 0.86 | ALDH1A1 (0.63) | ALDH1A1CYP1A2HPGDHSD17B10KDM4E | |
| SCHEMBL7233421 | 0.84 | NPC1 (0.54) | ALDH1A1CYP1A2HPGDHSD17B10KDM4E | |
| SCHEMBL2083552 | 0.83 | ALDH1A1 (0.47) | ALDH1A1CYP1A2HPGDHSD17B10KDM4E | |
| SCHEMBL2624097 | 0.82 | KDM4E (0.42) | ALDH1A1CYP1A2HPGDHSD17B10KDM4E | |
| SCHEMBL7237097 | 0.81 | ALDH1A1 (0.46) | ALDH1A1CYP1A2HPGDHSD17B10KDM4E | |
| SCHEMBL5209912 | 0.81 | ALDH1A1 (0.46) | ALDH1A1CYP1A2HPGDKDM4EGAA | |
| SCHEMBL244752 | 0.80 | ALDH1A1 (0.73) | ALDH1A1CYP1A2HPGDHSD17B10KDM4E | |
| SCHEMBL28720614 | 0.79 | L3MBTL1 (0.55) | ALDH1A1HPGDKDM4EGAAATM | |
| SCHEMBL3119761 | 0.79 | ALDH1A1 (1.00) | ALDH1A1CYP1A2HPGDHSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL8114168 | 0.79 | ALDH1A1 (0.71) | ALDH1A1CYP1A2HPGDHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108084111-B | Method for synthesizing amine compound containing sulfur and nitrogen heterocycles as drug intermediate | 烟台宁远药业有限公司 | 2020-09-04 | — | — | CN | claimed |
| US-20250084074-A1 | SUBSTITUTED HETEROCYCLES AS HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2025-03-13 | — | — | US | disclosed |
| CN-119421877-A | Substituted heterocyclic compounds as HSET inhibitors | 默克专利股份公司 | 2025-02-11 | — | — | CN | disclosed |
| EP-4463444-A1 | SUBSTITUTED HETEROCYCLES AS HSET INHIBITORS | Merck Patent GmbH (DE) | 2024-11-20 | — | — | EP | disclosed |
| WO-2023131690-A1 | SUBSTITUTED HETEROCYCLES AS HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2023-07-13 | — | — | WO | disclosed |
| CN-114057666-B | Synthesis method of 4, 5-disubstituted-2-aminothiazole compound | 沈阳药科大学 | 2023-02-07 | — | — | CN | disclosed |
| CN-114057666-A | Synthesis method of 4, 5-disubstituted-2-aminothiazole compound | 沈阳药科大学 | 2022-02-18 | — | — | CN | disclosed |
| CN-108084111-B | Method for synthesizing amine compound containing sulfur and nitrogen heterocycles as drug intermediate | 烟台宁远药业有限公司 | 2020-09-04 | — | — | CN | disclosed |
| EP-2432776-B1 | METHYL SULFANYL PYRIMIDINES USEFUL AS ANTIINFLAMMATORIES, ANALGESICS, AND ANTIEPILEPTICS | UNIV LAVAL (CA) | 2019-09-11 | — | — | EP | disclosed |
| EP-2417120-B1 | SUBSTITUTED PIPERIDINES AS CCR3 ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2016-10-26 | — | — | EP | disclosed |
| US-4602454-A | PLANT SAFENING AGENTS, SEEDS CHLOROACETAMIDE HERBICIDES | MONSANTO COMPANY (US) | 1986-07-29 | — | — | US | disclosed |
| US-4602937-A | PLANT SAFENING AGENTS, ACETAMIDE HERBICIDE | MONSANTO COMPANY (US) | 1986-07-29 | — | — | US | disclosed |
| WO-1986002646-A1 | NEW PICOLINE DERIVATIVES, PREPARATION PROCESS THEREOF, UTILIZATION THEREOF AND DRUGS CONTAINING THEM | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT M (DE) | 1986-05-09 | — | — | WO | disclosed |
| US-4586948-A | 2,4-disubstituted-5-thiazole-carboxylic acids and derivatives | MONSANTO COMPANY (US) | 1986-05-06 | — | — | US | disclosed |
| US-4437875-A | PLANT SAFENING AGENT FOR ACETAMIDE HERBICIDE | MONSANTO COMPANY (US) | 1984-03-20 | — | — | US | disclosed |
| US-4437876-A | PLANT SAFENING AGENTS FOR ACETAMIDE HERBICIDES | MONSANTO COMPANY (US) | 1984-03-20 | — | — | US | disclosed |
| EP-0027018-B1 | PROCESS FOR THE PRODUCTION OF 2-CHLORO-4-SUBSTITUTED-5-THIAZOLECARBOXYLATES | MONSANTO COMPANY (US) | 1983-10-05 | — | — | EP | disclosed |
| US-4308391-A | 2-Amino-4-substituted-thiazolecarboxylic acids and their derivatives | MONSANTO COMPANY (US) | 1981-12-29 | — | — | US | disclosed |
| EP-0027018-A1 | Process for the production of 2-chloro-4-substituted-5-thiazolecarboxylates | MONSANTO COMPANY (US) | 1981-04-15 | — | — | EP | disclosed |
| US-4199506-A | REDUCES HERBICIDAL INJURY TO PLATNS DUE TO ACETAMIDE HERBICIDES | MONSANTO COMPANY (US) | 1980-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250084074-A1 | SUBSTITUTED HETEROCYCLES AS HSET INHIBITORS | VHL, CDKN1A, CCNI | ALDH1A1 1680/4885CYP1A2 2245/4885HPGD 204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.