SCHEMBL244752

SCHEMBL244752

CCOC(=O)c1sc(N)nc1C

nearest known ligand 0.73

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.73
CYP1A2 P05177 1/20 0.73
HPGD P15428 3/20 0.67
HSD17B10 Q99714 2/20 0.60
LMNA P02545 2/20 0.54
CDC7 O00311 1/20 0.54
DBF4 Q9UBU7 1/20 0.54
MAPT P10636 3/20 0.53
NPC1 O15118 3/20 0.52
RAB9A P51151 2/20 0.51
KDM4E B2RXH2 1/20 0.51
TSHR P16473 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8114168 0.98 ALDH1A1 (0.71) ALDH1A1CYP1A2HPGDHSD17B10LMNA
SCHEMBL23372773 0.88 ALDH1A1 (0.58) ALDH1A1CYP1A2HPGDHSD17B10LMNA
SCHEMBL8484927 0.86 ALDH1A1 (0.56) ALDH1A1CYP1A2HPGDHSD17B10LMNA
SCHEMBL3921966 0.84 ALDH1A1 (0.71) ALDH1A1CYP1A2HPGDHSD17B10LMNA
SCHEMBL3119761 0.84 ALDH1A1 (1.00) ALDH1A1CYP1A2HPGDHSD17B10LMNA
SCHEMBL10532170 0.83 ALDH1A1 (0.57) ALDH1A1CYP1A2HPGDHSD17B10MAPT
SCHEMBL1552396 0.83 ALDH1A1 (0.69) ALDH1A1CYP1A2HPGDHSD17B10LMNA
SCHEMBL23703077 0.83 ALDH1A1 (0.69) ALDH1A1CYP1A2HPGDHSD17B10LMNA
SCHEMBL859765 0.83 ALDH1A1 (0.69) ALDH1A1CYP1A2HPGDHSD17B10LMNA
SCHEMBL276275 0.81 ALDH1A1 (0.62) ALDH1A1CYP1A2HPGDMAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 395 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120136809-A Febuxostat Process for the preparation of intermediates 无棣锐新医药化工有限公司 2025-06-13 CN claimed
CN-102942565-A 3,4-dichloro isothiazole derivatives, their preparation method and application JIANGXI TIANREN ECOLOGY CO LTD 2013-02-27 CN claimed
CN-102079732-A Method for synthesizing 2-amino-4-methylthiazole-5-carboxylate and derivatives thereof UNIV XI AN JIAOTONG 2011-06-01 CN claimed
US-12545654-B2 MYC inhibitors and uses thereof STEMSYNERGY THERAPEUTICS, INC. (US) 2026-02-10 US disclosed
US-12479809-B2 Hydrazone amide derivative and application thereof in preparation of medicaments for preventing and treating alopecia SHENZHEN CELL INSPIRE PHARMACEUTICAL DEVELOPMENT CO., LTD. (CN) 2025-11-25 US disclosed
CN-120136809-A Febuxostat Process for the preparation of intermediates 无棣锐新医药化工有限公司 2025-06-13 CN disclosed
CN-120136809-A Febuxostat Process for the preparation of intermediates 无棣锐新医药化工有限公司 2025-06-13 CN disclosed
WO-2025056690-A1 PARP1- AND IMMUNE-CHECKPOINT INHIBITORS FOR THE TREATMENT OF CANCER PATIENTS OVEREXPRESSING UBQLN1 AND/OR UBQLN4 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2025-03-20 WO disclosed
US-12252459-B2 Hydrazone amide derivatives and use thereof in preparation of anti-osteoporosis drugs SHENZHEN CELL INSPIRE PHARMACEUTICAL DEVELOPMENT CO., LTD. (CN) 2025-03-18 US disclosed
US-20250084074-A1 SUBSTITUTED HETEROCYCLES AS HSET INHIBITORS MERCK PATENT GMBH (DE) 2025-03-13 US disclosed
CN-119421877-A Substituted heterocyclic compounds as HSET inhibitors 默克专利股份公司 2025-02-11 CN disclosed
US-4424155-A 3-AMINO-1,2,4-OXADIAZOL-5-YL DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 1984-01-03 US disclosed
US-4325870-A DIAZOTIZATION, AMINATION CASSELLA AKTIENGESELLSCHAFT (DE) 1982-04-20 US disclosed
US-4154577-A Uniformly disperse dyed water-swellable cellulosic fibers BASF AKTIENGESELLSCHAFT (DE) 1979-05-15 US disclosed
US-4128545-A DISPERSE, POLYESTER BASF AKTIENGESELLSCHAFT (DE) 1978-12-05 US disclosed
US-4051099-A ISOINDOLES CIBA-GEIGY CORPORATION (US) 1977-09-27 US disclosed
US-4042578-A POLYESTERS BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) 1977-08-16 US disclosed
US-4016152-A SUITABLE FOR DYEING POLYESTERS BASF AKTIENGESELLSCHAFT (DT) 1977-04-05 US disclosed
US-3974123-A Dyes for thermoplastics BASF AKTIENGESELLSCHAFT (DT) 1976-08-10 US disclosed
US-3950321-A POLYESTERS BASF AKTIENGESELLSCHAFT (DT) 1976-04-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250084074-A1 SUBSTITUTED HETEROCYCLES AS HSET INHIBITORS VHL, CDKN1A, CCNI ALDH1A1 1680/4885CYP1A2 2245/4885HPGD 204/4885
US-12479809-B2 Hydrazone amide derivative and application thereof in preparation of medicaments for preventing and treating alopecia FH, HDGF, HRH4 ALDH1A1 652/4885CYP1A2 299/4885HPGD 33/4885
US-12252459-B2 Hydrazone amide derivatives and use thereof in preparation of anti-osteoporosis drugs SOST, HDAC5, PTH1R ALDH1A1 644/4885CYP1A2 265/4885HPGD 34/4885
US-12545654-B2 MYC inhibitors and uses thereof MYC, MYCBP, NR2E1 ALDH1A1 4317/4885CYP1A2 3304/4885HPGD 4763/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.