Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 6/20 | 0.72 |
| ▸ | BRD2 | P25440 | 3/20 | 0.72 |
| ▸ | BRD3 | Q15059 | 3/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17503238 | 1.00 | BRD4 (0.72) | BRD4BRD2BRD3 | |
| SCHEMBL5836512 | 1.00 | BRD4 (0.72) | BRD4BRD2BRD3 | |
| SCHEMBL17503239 | 1.00 | BRD4 (0.72) | BRD4BRD2BRD3 | |
| SCHEMBL224311 | 1.00 | BRD4 (0.72) | BRD4BRD2BRD3 | |
| SCHEMBL221888 | 0.92 | BRD4 (0.73) | BRD4BRD2BRD3 | |
| SCHEMBL2741188 | 0.92 | BRD4 (0.68) | BRD4BRD2BRD3 | |
| SCHEMBL13178434 | 0.91 | BRD4 (0.65) | BRD4BRD2BRD3 | |
| SCHEMBL221873 | 0.90 | BRD4 (0.72) | BRD4BRD2BRD3 | |
| SCHEMBL223302 | 0.89 | BRD4 (0.61) | BRD4BRD2BRD3 | |
| SCHEMBL222041 | 0.89 | BRD4 (0.71) | BRD4BRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3038621-B1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | HUMAN BIOMOLECULAR RES INSTITUTE (US) | 2020-12-02 | — | — | EP | claimed |
| US-11596716-B2 | Compounds and matrices for use in bone growth and repair | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2023-03-07 | — | — | US | disclosed |
| US-20210138117-A1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2021-05-13 | — | — | US | disclosed |
| US-10874766-B2 | Compounds and matrices for use in bone growth and repair | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2020-12-29 | — | — | US | disclosed |
| EP-3038621-B1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | HUMAN BIOMOLECULAR RES INSTITUTE (US) | 2020-12-02 | — | — | EP | disclosed |
| US-20160038641-A1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2016-02-11 | — | — | US | disclosed |
| US-7030246-B2 | Tetrahydroquinoline derivatives as stat6-modulators, preparation and use thereof | ASTRAZENECA AB (SE) | 2006-04-18 | — | — | US | disclosed |
| US-20040132724-A1 | Tetrahydroquinoline derivatives as stat6-modulators, preparation and use thereof | ASTRAZENECA AB (SE) | 2004-07-08 | — | — | US | disclosed |
| EP-1377553-A1 | TETRAHYDROQUINOLINE DERIVATIVES AS STAT6-MODULATORS, PREPARATION AND USE THEREOF | AstraZeneca AB (SE) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002079165-A1 | TETRAHYDROQUINOLINE DERIVATIVES AS STAT6-MODULATORS, PREPARATION AND USE THEREOF | ASTRAZENECA AB (SE) | 2002-10-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10874766-B2 | Compounds and matrices for use in bone growth and repair | BMP2, BMP4, BMP6 | BRD4 2279/4885BRD2 2362/4885BRD3 2435/4885 |
| US-11596716-B2 | Compounds and matrices for use in bone growth and repair | BMP2, BMP4, BMP6 | BRD4 2966/4885BRD2 3366/4885BRD3 3407/4885 |
| US-20210138117-A1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | BMP2, BMP4, BMP6 | BRD4 2966/4885BRD2 3366/4885BRD3 3407/4885 |
| US-20040132724-A1 | Tetrahydroquinoline derivatives as stat6-modulators, preparation and use thereof | STAT6, HRH4, HRH1 | BRD4 39/4885BRD2 153/4885BRD3 85/4885 |
| US-20160038641-A1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | BMP2, BMP4, BMP6 | BRD4 1630/4885BRD2 2208/4885BRD3 2144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.