Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2732854 | 0.74 | TSHR (0.45) | ALDH1A1TSHRHTTLMNAABCC4 | |
| SCHEMBL873725 | 0.74 | TSHR (0.45) | ALDH1A1TSHRHTTLMNAABCC4 | |
| SCHEMBL7773003 | 0.74 | TSHR (0.45) | ALDH1A1TSHRHTTLMNAABCC4 | |
| SCHEMBL5836398 | 0.74 | CYP2C19 (0.37) | ALDH1A1LMNAMAPT | |
| SCHEMBL10608081 | 0.72 | — | — | |
| SCHEMBL27593689 | 0.72 | ALDH1A1 (0.43) | ALDH1A1TSHRHTTLMNAABCC4 | |
| SCHEMBL770454 | 0.72 | ALDH1A1 (0.43) | ALDH1A1TSHRHTTLMNAABCC4 | |
| SCHEMBL10773383 | 0.72 | ALDH1A1 (0.43) | ALDH1A1TSHRHTTLMNAABCC4 | |
| SCHEMBL17818667 | 0.72 | ALDH1A1 (0.43) | ALDH1A1TSHRHTTLMNAABCC4 | |
| SCHEMBL528085 | 0.70 | TSHR (0.42) | ALDH1A1TSHRHTTLMNAABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005521-B1 | Catalytic compositions and methods for asymmetric allylic alkylation | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2006-02-28 | — | — | US | disclosed |
| US-6747152-B2 | COMPRISES MOLYBDENUM/TUNGSTEN/CHROMIUM COMPLEXES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2004-06-08 | — | — | US | disclosed |
| US-6541655-B2 | For use in regioselective and enantioselective alkylations of allylic substrates | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2003-04-01 | — | — | US | disclosed |
| US-6130349-A | USING COMPLEX OF MOLYBDENUM, TUNGSTEN OR CHROMIUM WITH 1,1*-BINAPHTHYL SYSTEM CONTAINING HETEROCYCLIC NITROGEN GROUP; ENANTIO- AND REGIOSELECTIVITY | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2000-10-10 | — | — | US | disclosed |