Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464479 | 0.87 | ALDH1A1 (0.41) | TSHRALDH1A1HTTLMNA | |
| SCHEMBL11000050 | 0.85 | ALDH1A1 (0.39) | TSHRALDH1A1HTTMAPT | |
| SCHEMBL13347371 | 0.79 | ALDH1A1 (0.39) | TSHRALDH1A1HTT | |
| SCHEMBL9503825 | 0.78 | ALDH1A1 (0.38) | TSHRALDH1A1HTT | |
| SCHEMBL2732854 | 0.77 | TSHR (0.45) | TSHRALDH1A1HTTLMNAABCC4 | |
| SCHEMBL873725 | 0.77 | TSHR (0.45) | TSHRALDH1A1HTTLMNAABCC4 | |
| SCHEMBL17818667 | 0.74 | ALDH1A1 (0.43) | TSHRALDH1A1HTTLMNAABCC4 | |
| SCHEMBL5836636 | 0.74 | ALDH1A1 (0.43) | TSHRALDH1A1HTTLMNAABCC4 | |
| SCHEMBL10608081 | 0.74 | — | — | |
| SCHEMBL770454 | 0.74 | ALDH1A1 (0.43) | TSHRALDH1A1HTTLMNAABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140155640-A1 | Surface Functionalised Nanoparticles | NANOCO TECHNOLOGIES LTD. (GB) | 2014-06-05 | — | — | US | disclosed |
| US-8394976-B2 | Surface functionalised nanoparticles | Nanoco Technologies, Ltd. (GB) | 2013-03-12 | — | — | US | disclosed |
| US-8394976-B2 | Surface functionalised nanoparticles | Nanoco Technologies, Ltd. (GB) | 2013-03-12 | — | — | US | disclosed |
| WO-2010052455-A1 | SURFACE FUNCTIONALISED NANOPARTICLES | NANOCO TECHNOLOGIES LTD (GB) | 2010-05-14 | — | — | WO | disclosed |
| US-20100113813-A1 | SURFACE FUNCTIONALISED NANOPARTICLES | NANOCO TECHNOLOGIES LIMITED (GB) | 2010-05-06 | — | — | US | disclosed |
| US-20100113813-A1 | SURFACE FUNCTIONALISED NANOPARTICLES | NANOCO TECHNOLOGIES LIMITED (GB) | 2010-05-06 | — | — | US | disclosed |
| US-20100068522-A1 | Surface Functionalised Nanoparticles | NANOCO TECHNOLOGIES LIMITED (GB) | 2010-03-18 | — | — | US | disclosed |
| WO-2001023471-A1 | HEAT STABLE ARTICLE, LATEX COMPOSITION, AND METHOD OF MAKING | THE DOW CHEMICAL COMPANY (US) | 2001-04-05 | — | — | WO | disclosed |
| EP-0395243-B1 | Inorganic particles | ICI PLC (GB) | 1994-01-19 | — | — | EP | disclosed |
| US-5064718-A | Precipitation in dipersant copolymer of acrylated polyether and acrylate monomer | IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) | 1991-11-12 | — | — | US | disclosed |
| EP-0435876-A1 | COMPOSITIONS AND METHODS TO VARY COLOR DENSITY. | ECOLAB INC (US) | 1991-07-10 | — | — | EP | disclosed |
| EP-0395243-A2 | Inorganic particles | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-10-31 | — | — | EP | disclosed |
| WO-1990002790-A1 | COMPOSITIONS AND METHODS TO VARY COLOR DENSITY | ECOLAB INC. (US) | 1990-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140155640-A1 | Surface Functionalised Nanoparticles | EPCAM, L1CAM, CD4 | TSHR 1512/4885ALDH1A1 1711/4885HTT 4750/4885 |
| US-20100113813-A1 | SURFACE FUNCTIONALISED NANOPARTICLES | CD47, CD63, EPCAM | TSHR 2354/4885ALDH1A1 1923/4885HTT 1976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.