SCHEMBL5836870

SCHEMBL5836870

CC1=NOC(c2c(S(C)(=O)=O)ccc(C(=O)c3cnn(C4CC4)c3O)c2Cl)C1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 3/20 0.33
NR3C1 P04150 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5837328 0.88
SCHEMBL27482264 0.82
SCHEMBL5836196 0.79 SMN1; SMN2 (0.33)
SCHEMBL5835636 0.78 EPAS1 (0.31)
SCHEMBL5836542 0.78 LMNA (0.33)
SCHEMBL1960627 0.76 HTT (0.32)
SCHEMBL6658568 0.71
SCHEMBL1961522 0.70 KDM4E (0.30)
SCHEMBL6605808 0.69 HDAC9 (0.31) GPR119
SCHEMBL5835530 0.67 L3MBTL1 (0.41) NR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7151075-B2 3-(4,5-Dihydroisoxazole-5-yl)benzoylpyrazole BASF AKTIENGESELLSCHAFT (DE) 2006-12-19 US disclosed
CN-1187349-C 3-(4.5-dihydroisoxazole-5-yl)-benzoylpyrazole BASF AG (DE) 2005-02-02 CN disclosed
EP-1240163-B1 3-(4,5-DIHYDROISOXAZOLE-5-YL)BENZOYLPYRAZOLE BASF AG (DE) 2004-03-31 EP disclosed
CN-1413209-A 3-(4.5-dihydroisoxazole-5-yl)-benzoylpyrazole BASF AG (DE) 2003-04-23 CN disclosed