Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | GLP1R | P43220 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5836196 | 0.87 | SMN1; SMN2 (0.33) | L3MBTL1MAPTHSD17B10NPSR1NPC1 | |
| SCHEMBL5836542 | 0.76 | LMNA (0.33) | LMNA | |
| SCHEMBL5835636 | 0.76 | EPAS1 (0.31) | — | |
| SCHEMBL19810174 | 0.72 | ALDH1A1 (0.44) | L3MBTL1ALDH1A1CYP3A4CYP2C19POLB | |
| SCHEMBL5996915 | 0.71 | ALDH1A1 (0.51) | L3MBTL1ALDH1A1CYP3A4CYP2C19POLB | |
| SCHEMBL5997134 | 0.69 | ALDH1A1 (0.46) | L3MBTL1ALDH1A1CYP3A4CYP2C19POLB | |
| SCHEMBL4267446 | 0.69 | HTT (0.34) | POLBHTTLMNAMAPTNPSR1 | |
| SCHEMBL5994480 | 0.69 | ALDH1A1 (0.48) | L3MBTL1ALDH1A1CYP3A4CYP2C19POLB | |
| SCHEMBL21179401 | 0.68 | TSHR (0.46) | ALDH1A1HTTLMNAMAPTHSD17B10 | |
| SCHEMBL30599579 | 0.68 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1CYP3A4CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7151075-B2 | 3-(4,5-Dihydroisoxazole-5-yl)benzoylpyrazole | BASF AKTIENGESELLSCHAFT (DE) | 2006-12-19 | — | — | US | disclosed |
| US-6645919-B1 | Nonphytotoxic to crops | BASF AKTIENGESELLSCHAFT (DE) | 2003-11-11 | — | — | US | disclosed |
| US-20030199699-A1 | 3-(4,5-Dihydroisoxaxol-5-yl)benzoylcyclohexenones and the use thereof as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 2003-10-23 | — | — | US | disclosed |
| US-20030100590-A1 | 3-(4,5-dihydroisoxazol-5-yl)benzoylpyrazole | BASF AKTIENGESELLSCHAFT (DE) | 2003-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199699-A1 | 3-(4,5-Dihydroisoxaxol-5-yl)benzoylcyclohexenones and the use thereof as herbicides | CBR3, HDHD5, CBR1 | L3MBTL1 1367/4885ALDH1A1 403/4885CYP3A4 600/4885 |
| US-20030100590-A1 | 3-(4,5-dihydroisoxazol-5-yl)benzoylpyrazole | CBR3, CBR1, DHX35 | L3MBTL1 639/4885ALDH1A1 516/4885CYP3A4 626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.