SCHEMBL5837005

SCHEMBL5837005

CCC(CC1C(C)=Cc2c(-c3cccc4ccccc34)cccc21)C1C(C)=Cc2c(-c3cccc4ccccc34)cccc21

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.31
PPARA Q07869 1/20 0.31
MAPT P10636 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8469174 0.88 KDM4E (0.36)
SCHEMBL5836290 0.84 PDCD1 (0.31)
SCHEMBL5836758 0.83 AKR1C3 (0.32)
SCHEMBL7039658 0.80 ALDH1A1 (0.36) MAPTNPSR1
SCHEMBL4622950 0.80 ALDH1A1 (0.36) MAPTNPSR1
SCHEMBL7781565 0.79 CYP1A2 (0.40) MAPT
SCHEMBL3996671 0.79 SLC6A4 (0.35) MAPTNPSR1
SCHEMBL8072255 0.79 MAPT (0.36) PPARGPPARAMAPTNPSR1
SCHEMBL8678964 0.77 ALDH1A1 (0.34) MAPTNPSR1
SCHEMBL1241803 0.76 ALDH1A1 (0.33) MAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6984743-B1 Method for producing metallocenes BASELL POLYOLEFINE GMBH (DE) 2006-01-10 US disclosed
EP-1015463-B1 METHOD FOR PRODUCING METALLOCENES BASELL POLYOLEFINE GMBH (DE) 2002-12-11 EP disclosed