SCHEMBL5837477

SCHEMBL5837477

CCCCOC(=O)C1(CC(=O)O)CC2C=CC1C2

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
TSHR P16473 2/20 0.33
HPGD P15428 1/20 0.33
ALDH1A1 P00352 1/20 0.33
ADAM17 P78536 1/20 0.31
HCAR2 Q8TDS4 1/20 0.31
EPHX2 P34913 4/20 0.31
ATM Q13315 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ESR1 P03372 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5836209 0.92 CYP2D6 (0.35) CYP2D6CYP2C19ALDH1A1
SCHEMBL5836998 0.88 EPHX2 (0.34) CYP2D6CYP2C19TSHRALDH1A1ADAM17
SCHEMBL5837506 0.87 CYP2D6 (0.36) CYP2D6CYP2C19ADAM17
SCHEMBL5837771 0.82 EPHX2 (0.36) CYP2D6CYP2C19ALDH1A1HCAR2EPHX2
SCHEMBL5836347 0.81 CYP2D6 (0.35) CYP2D6CYP2C19ADAM17
SCHEMBL7204575 0.80 CYP2C19 (0.37) CYP2D6CYP2C19TSHRHPGDALDH1A1
SCHEMBL5836367 0.80 CYP2D6 (0.33) CYP2D6CYP2C19EPHX2
SCHEMBL200578 0.79 CYP2C19 (0.36) CYP2D6CYP2C19TSHRHPGDALDH1A1
SCHEMBL15611830 0.79 EPHX2 (0.40) CYP2D6CYP2C19EPHX2
SCHEMBL15611567 0.78 NAAA (0.41) EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100386357-C Norbornene-based ring-opening polymerization polymer, product of hydrogenation of norbornene-based ring-opening polymerization polymer, and processes for producing these ZEON CORP (JP) 2008-05-07 CN disclosed
US-7037993-B2 Norbornene-based ring-opening polymerization polymer, product of hydrogenation of norbornene-based ring-opening polymerization polymer, and processes for producing these ZEON CORPORATION (JP) 2006-05-02 US disclosed
CN-1659205-A Norbornene-based ring-opening polymer, hydrogenation product of norbornene-based ring-opening polymer, and method for producing same ZEON CORP (JP) 2005-08-24 CN disclosed
US-20050148746-A1 Norbornene-based ring-opening polymerization polymer, product of hydrogenation of norbornene-based ring-opening polymerization polymer, and processes for producing these ZEON CORPORATION (JP) 2005-07-07 US disclosed