Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10358243 | 0.78 | KEAP1 (0.36) | KEAP1NFE2L2CES2CES1GRM2 | |
| SCHEMBL2535863 | 0.77 | GRM2 (0.45) | KEAP1NFE2L2GRM2GRM3 | |
| SCHEMBL29142969 | 0.76 | KEAP1 (0.37) | KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL19150278 | 0.75 | ALDH1A1 (0.40) | KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL19148259 | 0.75 | ALDH1A1 (0.40) | KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL2846765 | 0.74 | KEAP1 (0.42) | KEAP1NFE2L2CES2CES1GRM2 | |
| SCHEMBL873007 | 0.74 | KEAP1 (0.42) | KEAP1NFE2L2CES2CES1GRM2 | |
| SCHEMBL2232704 | 0.72 | ALDH1A1 (0.37) | KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL668614 | 0.72 | ALDH1A1 (0.42) | KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL19148633 | 0.72 | ALDH1A1 (0.42) | KEAP1NFE2L2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409439-B1 | A PROCESS FOR THE ISOMERIZATION OF AN OLEFIN | SHELL INT RESEARCH (NL) | 2015-04-15 | — | — | EP | disclosed |
| US-20060183954-A1 | Process for the isomerization of an olefin | DOLL MICHAEL J | 2006-08-17 | — | — | US | disclosed |
| US-7078579-B2 | Process for the isomerization of a vinylidene olefin | SHELL OIL COMPANY (US) | 2006-07-18 | — | — | US | disclosed |
| EP-1414773-A1 | A PROCESS FOR THE ISOMERIZATION OF A VINYLIDENE OLEFIN | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 2004-05-06 | — | — | EP | disclosed |
| EP-1409439-A1 | A PROCESS FOR THE ISOMERIZATION OF AN OLEFIN | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 2004-04-21 | — | — | EP | disclosed |
| US-20030009071-A1 | Process for the isomerization of a vinylidene olefin | SHELL OIL COMPANY | 2003-01-09 | — | — | US | disclosed |
| WO-2003000630-A1 | A PROCESS FOR THE ISOMERIZATION OF A VINYLIDENE OLEFIN | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2003-01-03 | — | — | WO | disclosed |
| WO-2003000631-A1 | A PROCESS FOR THE ISOMERIZATION OF AN OLEFIN | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2003-01-03 | — | — | WO | disclosed |
| US-4284837-A | MINIMIZING BY-PRODUCTS BY CONTACTING WITH AN ALKALI METAL HYDROXIDE | SHELL OIL COMPANY (US) | 1981-08-18 | — | — | US | disclosed |