Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
| ▸ | ACLY | P53396 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29142969 | 0.98 | KEAP1 (0.37) | KEAP1NFE2L2ALDH1A1CYP2D6TSHR | |
| SCHEMBL1999867 | 0.80 | EPHX2 (0.38) | ALDH1A1CYP2D6CYP2C19EPHX2EPHX1 | |
| SCHEMBL20168656 | 0.80 | KEAP1 (0.37) | KEAP1NFE2L2ALDH1A1CYP2D6TSHR | |
| SCHEMBL19148259 | 0.79 | ALDH1A1 (0.40) | KEAP1NFE2L2ALDH1A1EPHX2LMNA | |
| SCHEMBL19150278 | 0.79 | ALDH1A1 (0.40) | KEAP1NFE2L2ALDH1A1EPHX2LMNA | |
| SCHEMBL5838100 | 0.78 | KEAP1 (0.36) | KEAP1NFE2L2ALDH1A1CES2CES1 | |
| SCHEMBL31352036 | 0.77 | ALDH1A1 (0.36) | KEAP1NFE2L2ALDH1A1CYP2D6TSHR | |
| SCHEMBL2579739 | 0.77 | ALDH1A1 (0.36) | KEAP1NFE2L2ALDH1A1CYP2D6TSHR | |
| SCHEMBL2232704 | 0.77 | ALDH1A1 (0.37) | KEAP1NFE2L2ALDH1A1EPHX2LMNA | |
| SCHEMBL2535863 | 0.77 | GRM2 (0.45) | KEAP1NFE2L2CYP2D6EPHX2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107075011-B | Magnesium dichloride-ethanol adducts and catalyst components obtained therefrom | 巴塞尔聚烯烃意大利有限公司 | 2019-11-12 | — | — | CN | disclosed |
| CN-108602912-A | Pre-activated catalyst component for olefinic polymerization | 巴塞尔聚烯烃股份有限公司 | 2018-09-28 | — | — | CN | disclosed |
| CN-107075011-A | Magnesium dichloride-ethanol adducts and catalyst components obtained therefrom | 巴塞尔聚烯烃意大利有限公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-104470954-B | Magnesium chloride ethanol adducts and catalytic component therefrom | 巴塞尔聚烯烃意大利有限公司 | 2017-07-11 | — | — | CN | disclosed |
| CN-105636994-A | Process for the preparation of porous propylene polymers | BASELL POLIOLEFINE ITALIA SRL | 2016-06-01 | — | — | CN | disclosed |
| CN-105408112-A | Heat-sealable polyolefin films and sheets | BASELL POLIOLEFINE ITALIA SPA | 2016-03-16 | — | — | CN | disclosed |
| CN-104285170-A | Optical film, polarizing plate, and liquid crystal display device | FUJIFILM CORP | 2015-01-14 | — | — | CN | disclosed |
| US-8747540-B2 | Cellulose ester film, polarizing plate, liquid crystal display device, and method for manufacturing the cellulose ester film | FUJIFILM CORPORATION (JP) | 2014-06-10 | — | — | US | disclosed |
| US-20120204758-A1 | CELLULOSE ESTER FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE, AND METHOD FOR MANUFACTURING THE CELLULOSE ESTER FILM | FUJIFILM CORPORATION (JP) | 2012-08-16 | — | — | US | disclosed |
| EP-0190424-B1 | PROCESS FOR THE PREPARATION OF PURE DIALKYL SUCCINATES | Chemie Linz Gesellschaft m.b.H. (AT) | 1990-10-17 | — | — | EP | disclosed |
| EP-0190424-A2 | Process for the preparation of pure dialkyl succinates | Chemie Linz Gesellschaft m.b.H. (AT) | 1986-08-13 | — | — | EP | disclosed |