SCHEMBL5838462

SCHEMBL5838462

Cc1cn([C@H]2CC(OC(=O)CCC(=O)NCCNC(=O)c3cc(C(=O)NCCNC(=O)CCC(=O)OC4C[C@H](n5cc(C)c(=O)[nH]c5=O)O[C@@H]4CO)cc(C(=O)NCCNC(=O)CCC(=O)OC4C[C@H](n5cc(C)c(=O)[nH]c5=O)O[C@@H]4CO)c3)[C@@H](CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.60

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RNASE1 P07998 1/20 0.60
TK2 O00142 1/20 0.51
SLC6A2 P23975 1/20 0.48
TK1 P04183 4/20 0.48
LMNA P02545 2/20 0.47
TSHR P16473 2/20 0.47
ALB P02768 1/20 0.47
PKM P14618 1/20 0.47
BLM P54132 1/20 0.47
PMP22 Q01453 1/20 0.47
CYP2D6 P10635 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23394587 0.88 RNASE1 (0.59) RNASE1TK2SLC6A2TK1LMNA
SCHEMBL5838118 0.86 RNASE1 (0.55) RNASE1TK2SLC6A2TK1LMNA
SCHEMBL23914022 0.86 RNASE1 (0.57) RNASE1TK2SLC6A2TK1LMNA
SCHEMBL19407973 0.85 RNASE1 (0.71) RNASE1TK2SLC6A2TK1LMNA
SCHEMBL3337696 0.85 RNASE1 (0.71) RNASE1TK2SLC6A2TK1LMNA
SCHEMBL774263 0.83 RNASE1 (0.68) RNASE1TK2SLC6A2TK1LMNA
SCHEMBL14681227 0.83 RNASE1 (0.68) RNASE1TK2SLC6A2TK1LMNA
SCHEMBL16287348 0.83 RNASE1 (0.68) RNASE1TK2SLC6A2TK1LMNA
SCHEMBL767324 0.83 RNASE1 (0.68) RNASE1TK2SLC6A2TK1LMNA
SCHEMBL16349867 0.83 RNASE1 (0.71) RNASE1TK2SLC6A2TK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7038103-B2 Solution phase biopolymer synthesis HUBERT KOSTER (CH) 2006-05-02 US claimed
US-20020016451-A1 SOLUTION PHASE BIOPOLYMER SYNTHESIS CAPROTEC BIOANALYTICS GMBH (DE) 2002-02-07 US claimed
US-20020007048-A1 Solution Phase Biopolymer Synthesis CAPROTEC BIOANALYTICS GMBH (DE) 2002-01-17 US claimed
US-7094943-B2 Solution phase biopolymer synthesis Köster, Hubert (US) 2006-08-22 US disclosed
US-7038103-B2 Solution phase biopolymer synthesis HUBERT KOSTER (CH) 2006-05-02 US disclosed
US-20020016451-A1 SOLUTION PHASE BIOPOLYMER SYNTHESIS CAPROTEC BIOANALYTICS GMBH (DE) 2002-02-07 US disclosed
US-20020007048-A1 Solution Phase Biopolymer Synthesis CAPROTEC BIOANALYTICS GMBH (DE) 2002-01-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020007048-A1 Solution Phase Biopolymer Synthesis RNGTT, SGMS1, SPNS2 RNASE1 195/4885TK2 1942/4885SLC6A2 1887/4885
US-20020016451-A1 SOLUTION PHASE BIOPOLYMER SYNTHESIS RNGTT, SGMS1, SPNS2 RNASE1 195/4885TK2 1942/4885SLC6A2 1887/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.