SCHEMBL767324

SCHEMBL767324

CC(=O)CCC(=O)O[C@H]1C[C@H](n2cc(C)c(=O)[nH]c2=O)O[C@@H]1CO

nearest known ligand 0.68

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RNASE1 P07998 1/20 0.68
TK1 P04183 5/20 0.57
SLC6A2 P23975 1/20 0.56
LMNA P02545 2/20 0.55
TSHR P16473 2/20 0.55
ALB P02768 1/20 0.55
PKM P14618 1/20 0.55
BLM P54132 1/20 0.55
PMP22 Q01453 1/20 0.55
CYP2D6 P10635 1/20 0.55
TK2 O00142 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL774263 1.00 RNASE1 (0.68) RNASE1TK1SLC6A2LMNATSHR
SCHEMBL14681227 1.00 RNASE1 (0.68) RNASE1TK1SLC6A2LMNATSHR
SCHEMBL16287348 1.00 RNASE1 (0.68) RNASE1TK1SLC6A2LMNATSHR
SCHEMBL3337696 0.92 RNASE1 (0.71) RNASE1TK1SLC6A2LMNATSHR
SCHEMBL19407973 0.92 RNASE1 (0.71) RNASE1TK1SLC6A2LMNATSHR
SCHEMBL13901238 0.92 RNASE1 (0.71) RNASE1TK1SLC6A2LMNAALB
SCHEMBL16349867 0.92 RNASE1 (0.71) RNASE1TK1SLC6A2LMNAALB
SCHEMBL5180425 0.90 ABCG2 (0.59) RNASE1TK1
SCHEMBL4099261 0.89 TK1 (0.61) RNASE1TK1SLC6A2LMNATSHR
SCHEMBL265601 0.89 RNASE1 (0.74) RNASE1TK1LMNATSHRALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12415835-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-16 US disclosed
US-20240166689-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-05-23 US disclosed
US-11891457-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-02-06 US disclosed
US-11548910-B2 Oligonucleotide production method NISSAN CHEMICAL CORPORATION (JP) 2023-01-10 US disclosed
EP-3974563-A1 CYCLIC PEPTIDES Chugai Seiyaku Kabushiki Kaisha (JP) 2022-03-30 EP disclosed
EP-2813512-B1 PEPTIDE-COMPOUND CYCLIZATION METHOD CHUGAI PHARMACEUTICAL CO LTD (JP) 2021-03-31 EP disclosed
US-20210061860-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2021-03-04 US disclosed
US-20210061860-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2021-03-04 US disclosed
US-20190169223-A1 OLIGONUCLEOTIDE PRODUCTION METHOD NISSAN CHEMICAL CORPORATION (JP) 2019-06-06 US disclosed
EP-3378869-A1 METHOD FOR PRODUCING OLIGONUCLEOTIDE Nissan Chemical Corporation (JP) 2018-09-26 EP disclosed
US-5646260-A PHOSPHORYLATED OLIGONUCLEOTIDES LETSINGER ROBERT L (US) 1997-07-08 US disclosed
WO-1997019092-A1 IMPROVED PROCESS FOR THE SYNTHESIS OF OLIGOMERIC COMPOUNDS ISIS PHARMACEUTICALS, INC. (US) 1997-05-29 WO disclosed
EP-0678096-B1 SYNTHESIS OF DIMMER BLOCKS AND THEIR USE IN ASSEMBLING OLIGONUCLEOTIDES HYBRIDON INC (US) 1997-03-19 EP disclosed
US-5476925-A Antisense agents NORTHWESTERN UNIVERSITY (US) 1995-12-19 US disclosed
US-5218102-A Easily synthesized, hybridize well with target sequences IMPROBIO (BE) 1993-06-08 US disclosed
US-4973679-A Process for oligonucleo tide synthesis using phosphormidite intermediates UNIVERSITY PATENTS, INC. (US) 1990-11-27 US disclosed
US-4668777-A POLYNUCLEOTIDE INTERMEDIATES UNIVERSITY PATENTS, INC. (US) 1987-05-26 US disclosed
EP-0061746-B1 PHOSPHORAMIDITE COMPOUNDS AND THEIR USE IN PRODUCING OLIGONUCLEOTIDES UNIVERSITY PATENTS, INC. (US) 1985-03-20 EP disclosed
US-4415732-A STORAGE-STABLE NUCLEOSIDES; POLYNUCLEOTIDE SYNTHESIS UNIVERSITY PATENTS, INC. (US) 1983-11-15 US disclosed
EP-0061746-A1 Phosphoramidite compounds and their use in producing oligonucleotides UNIVERSITY PATENTS, INC. (US) 1982-10-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11891457-B2 Peptide-compound cyclization method VIP, NGLY1, GLP1R RNASE1 1089/4885TK1 3864/4885SLC6A2 4756/4885
US-20210061860-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD VIP, NGLY1, GLP1R RNASE1 1089/4885TK1 3864/4885SLC6A2 4756/4885
US-20240166689-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD VIP, NGLY1, GLP1R RNASE1 1089/4885TK1 3864/4885SLC6A2 4756/4885
US-11548910-B2 Oligonucleotide production method RNGTT, OSGEP, PHAX RNASE1 301/4885TK1 183/4885SLC6A2 3077/4885
US-20190169223-A1 OLIGONUCLEOTIDE PRODUCTION METHOD RNGTT, OSGEP, PHAX RNASE1 301/4885TK1 183/4885SLC6A2 3077/4885
US-12415835-B2 Peptide-compound cyclization method VIP, NGLY1, GLP1R RNASE1 1089/4885TK1 3864/4885SLC6A2 4756/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.