Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | NNMT | P40261 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CCR1 | P32246 | 2/20 | 0.47 |
| ▸ | CCR5 | P51681 | 2/20 | 0.47 |
| ▸ | CCR8 | P51685 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10169399 | 0.81 | NPSR1 (0.45) | NPSR1RXFP1ALDH1A1KDM4ELMNA | |
| SCHEMBL22584043 | 0.79 | GRM5 (0.51) | NPSR1RXFP1ALDH1A1KDM4EALOX15 | |
| SCHEMBL2815367 | 0.77 | NPSR1 (0.47) | NPSR1RXFP1ALDH1A1KDM4EGRM5 | |
| SCHEMBL18765298 | 0.76 | NPSR1 (0.46) | NPSR1RXFP1ALDH1A1KDM4ELMNA | |
| SCHEMBL29933397 | 0.76 | PARP1 (0.67) | NPSR1RXFP1KDM4ELMNACCR1 | |
| SCHEMBL11927613 | 0.74 | KDM4E (0.59) | NPSR1ALDH1A1KDM4ELMNACCR1 | |
| SCHEMBL22468488 | 0.74 | BTK (0.46) | NPSR1RXFP1KDM4ELMNACCR1 | |
| SCHEMBL22468497 | 0.74 | BTK (0.58) | NPSR1RXFP1ALDH1A1KDM4ETP53 | |
| SCHEMBL12272145 | 0.74 | NNMT (0.46) | RXFP1ALDH1A1NNMTSMN1; SMN2BTK | |
| SCHEMBL935065 | 0.73 | KDM4E (0.59) | NPSR1RXFP1ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732566-A2 | 6-AZAINDOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005097129-A2 | 6-AZAINDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-10-20 | — | — | WO | disclosed |