Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.40 |
| ▸ | TTPA | P49638 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 3/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | PHLPP1 | O60346 | 1/20 | 0.34 |
| ▸ | ILK | Q13418 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6681011 | 0.83 | ALOX5 (0.36) | MAPTLMNAMEN1GSTP1TTPA | |
| SCHEMBL7046202 | 0.81 | ALOX5 (0.36) | MAPTLMNAMEN1GSTP1TTPA | |
| SCHEMBL5838490 | 0.77 | ALOX5 (0.36) | MAPTLMNAMEN1GSTP1TTPA | |
| SCHEMBL6677365 | 0.77 | ALOX5 (0.34) | MAPTLMNAMEN1GSTP1TTPA | |
| Methylamine SCHEMBL27904384 | 0.75 | TTPA (0.62) | MAPTLMNAMEN1GSTP1TTPA | |
| SCHEMBL5839617 | 0.75 | CYP4F2 (0.35) | MAPTLMNAMEN1GSTP1TTPA | |
| SCHEMBL2140164 | 0.75 | MAPT (0.65) | MAPTLMNAMEN1GSTP1TTPA | |
| SCHEMBL13247544 | 0.75 | MAPT (0.65) | MAPTLMNAMEN1GSTP1TTPA | |
| SCHEMBL20024669 | 0.75 | MAPT (0.65) | MAPTLMNAMEN1GSTP1TTPA | |
| SCHEMBL14521827 | 0.75 | MAPT (0.65) | MAPTLMNAMEN1GSTP1TTPA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7115657-B2 | Bifunctional agents possessing antioxidant and antiarrhythmic activity | UNI-PHARMA KLEON TSETIS PHARMACEUTICAL LABORATORIES S.A. (GR) | 2006-10-03 | — | — | US | disclosed |
| US-20040259763-A1 | Bifunctional agents possessing antioxidant and antiarrhythmic activity | UNI-PHARMA KLEON TSETIS PHARMACEUTICAL LABORATORIES S.A. (GR) | 2004-12-23 | — | — | US | disclosed |
| EP-1301504-B1 | BIFUNCTIONAL AGENTS POSSESSING ANTIOXIDANT AND ANTIARRHYTHMIC ACTIVITY | UNI PHARMA KLEON TSETIS PHARMACEUTICAL LAB SA (GR) | 2004-11-03 | — | — | EP | disclosed |
| EP-1301504-A1 | BIFUNCTIONAL AGENTS POSSESSING ANTIOXIDANT AND ANTIARRHYTHMIC ACTIVITY | Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A. (GR) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002004438-A1 | BIFUNCTIONAL AGENTS POSSESSING ANTIOXIDANT AND ANTIARRHYTHMIC ACTIVITY | UNI-PHARMA KLEON TSETIS PHARMACEUTICAL LABORATORIES S.A. (GR) | 2002-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259763-A1 | Bifunctional agents possessing antioxidant and antiarrhythmic activity | GPX4, GSR, GPX1 | MAPT 4885/4885LMNA 1688/4885MEN1 4378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.