Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL999848 | 0.75 | TSHR (0.41) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL5839108 | 0.74 | ALDH1A1 (0.35) | TSHRALDH1A1 | |
| SCHEMBL4595068 | 0.70 | TSHR (0.40) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL11804015 | 0.70 | TSHR (0.37) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL9715015 | 0.70 | TSHR (0.42) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL374777 | 0.69 | TSHR (0.43) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL11802045 | 0.69 | TSHR (0.36) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL3446806 | 0.68 | TSHR (0.39) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL4596155 | 0.68 | TSHR (0.42) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL7267949 | 0.67 | TSHR (0.40) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7037954-B2 | Ocular lens material | MENICON CO., LTD. (JP) | 2006-05-02 | — | — | US | disclosed |
| EP-1197782-B1 | MATERIAL FOR OCULAR LENS | MENICON CO LTD (JP) | 2004-06-02 | — | — | EP | disclosed |
| US-20040039077-A1 | Ocular lens material | MENICON CO., LTD. | 2004-02-26 | — | — | US | disclosed |
| US-6638991-B2 | Lens material comprising a copolymer derived from a polysiloxane endcapped with acrylated urethane groups, a silicon-containing alkyl methacrylate, a hydrophilic monomer, and a crosslinking monomer; oxygen permeability, strength | MENICON CO., LTD. (JP) | 2003-10-28 | — | — | US | disclosed |
| US-20020198280-A1 | Material for ocular lens | MENICON CO., LTD. (JP) | 2002-12-26 | — | — | US | disclosed |
| EP-1197782-A1 | MATERIAL FOR OCULAR LENS | MENICON CO., LTD. (JP) | 2002-04-17 | — | — | EP | disclosed |