Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 4/20 | 0.78 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1042453 | 0.88 | CES1 (1.00) | CES1KMT2AMEN1HDAC8HDAC6 | |
| SCHEMBL5709778 | 0.88 | CES1 (1.00) | CES1KMT2AMEN1HDAC8HDAC6 | |
| SCHEMBL583919 | 0.81 | FFAR1 (0.65) | CES1LMNAABCC4GAATSHR | |
| SCHEMBL12895712 | 0.81 | LMNA (0.62) | CES1LMNAABCC4GAATSHR | |
| SCHEMBL10431529 | 0.78 | CES1 (0.67) | CES1LMNA | |
| SCHEMBL28262050 | 0.77 | CES1 (0.56) | CES1LMNAABCC4GAATSHR | |
| Felbinac SCHEMBL26084 | 0.77 | LMNA (1.00) | LMNAABCC4GAATSHRPTGS1 | |
| SCHEMBL11879591 | 0.77 | LMNA (0.75) | CES1LMNAABCC4GAATSHR | |
| SCHEMBL2381708 | 0.76 | CES1 (0.69) | CES1LMNAPTGS1HDAC6FFAR1 | |
| SCHEMBL17073597 | 0.76 | CES1 (0.64) | CES1LMNAGAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108572-A | Synthesis method of alkyl trifluoromethyl compounds | 合肥工业大学 | 2024-05-31 | — | — | CN | disclosed |
| EP-2417216-A2 | MODIFICATION OF LAYERED SILICATES FOR LUMINESCENCE ACTIVATION | Inbio Prof. Jürgen Büddefeld Dr. Peter Klauth Prof. Manfred Rietz Gbr (DE) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010115503-A2 | MODIFICATION OF LAYERED SILICATES FOR LUMINESCENCE ACTIVATION | INBIO PROF. JÜRGEN BÜDDEFELD DR. PETER KLAUTH PROF. MANFRED RIETZ GBR (DE) | 2010-10-14 | — | — | WO | disclosed |