Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10431529 | 0.81 | CES1 (0.67) | CES1NPC1RAB9ACTBP2LMNA | |
| SCHEMBL1477511 | 0.79 | L3MBTL1 (0.54) | NPC1RAB9ACTBP2CNR2L3MBTL1 | |
| SCHEMBL28268026 | 0.79 | CES1 (0.64) | CES1NPC1RAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL17073597 | 0.79 | CES1 (0.64) | CES1NPC1RAB9ACTBP2L3MBTL1 | |
| SCHEMBL28264746 | 0.79 | CES1 (0.64) | CES1 | |
| SCHEMBL1042453 | 0.78 | CES1 (1.00) | CES1MEN1KMT2A | |
| SCHEMBL5709778 | 0.78 | CES1 (1.00) | CES1MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL5659578 | 0.77 | CA2 (0.50) | CES1NPC1RAB9ACTBP2CNR2 | |
| SCHEMBL29475161 | 0.77 | CES1 (0.61) | CES1CTBP2SMN1; SMN2PIK3CAMEN1 | |
| SCHEMBL28265966 | 0.77 | CES1 (0.61) | CES1CTBP2SMN1; SMN2PIK3CAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118772034-A | Preparation process of 2-p-chlorophenyl-5- (trifluoromethyl) pyrrole-3-nitrile | 山东亿嘉农化有限公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-104016899-A | Synthetic method for chlorfenapyr | UNIV ZHEJIANG NORMAL | 2014-09-03 | — | — | CN | disclosed |
| EP-0481182-B1 | Bis- and tris(trifluoromethyl) arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID CO (US) | 1997-01-29 | — | — | EP | disclosed |
| EP-0485716-B1 | Process for the preparation of insecticidal, acaricidal and nematicidal 4-substituted-5-(trifluoromethyl)pyrrole-3-carbonitrile compounds | AMERICAN CYANAMID CO (US) | 1996-02-28 | — | — | EP | disclosed |
| US-5281719-A | Reacting a methyl N-((trimethylsilyl)methyl)thiobenzimidate with 2,3-dichloro-hexafluorobutene to give a 2-aryl-3,4-bis-(trifluoromethyl)pyrrole and reacting this with a halogenating compound | AMERICAN CYANAMID COMPANY (US) | 1994-01-25 | — | — | US | disclosed |
| US-5229524-A | Bis-and tris (trifluoromethyl) arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID COMPANY (US) | 1993-07-20 | — | — | US | disclosed |
| US-5157047-A | Miticides | AMERICAN CYANAMID COMPANY (US) | 1992-10-20 | — | — | US | disclosed |
| EP-0485716-A1 | Process for the preparation of insecticidal, acaricidal and nematicidal 4-substituted-5-(trifluoromethyl)pyrrole-3-carbonitrile compounds | AMERICAN CYANAMID COMPANY (US) | 1992-05-20 | — | — | EP | disclosed |
| EP-0481182-A1 | Bis- and tris(trifluoromethyl) arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID COMPANY (US) | 1992-04-22 | — | — | EP | disclosed |
| US-5106985-A | PROCESS FOR THE PREPARATION OF INSECTICIDAL, NEMATICIDAL AND ACARICIDAL 4-SUBSTITUTED-5-(TRIFLUOROMETHYL)PYRROLE-3-CARBONITRILE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 1992-04-21 | — | — | US | disclosed |
| US-4859699-A | Substituted N-benzoyl-N'-thienylureas | SANDOZ LTD. (CH) | 1989-08-22 | — | — | US | disclosed |
| EP-0300972-A1 | Substituted N-benzoyl-N'-thienyl ureas, and their use as insecticides | SANDOZ AG (CH) | 1989-01-25 | — | — | EP | disclosed |