Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 2/20 | 0.68 |
| ▸ | FABP4 | P15090 | 2/20 | 0.68 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.68 |
| ▸ | RXRA | P19793 | 1/20 | 0.57 |
| ▸ | RXRB | P28702 | 1/20 | 0.57 |
| ▸ | RXRG | P48443 | 1/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.56 |
| ▸ | THRA | P10827 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | XBP1 | P17861 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5664028 | 0.90 | FABP3 (0.66) | FABP3FABP4FABP5RXRARXRB | |
| SCHEMBL1388211 | 0.89 | PTGER1 (0.60) | FABP3FABP4FABP5RXRARXRB | |
| SCHEMBL1096673 | 0.86 | RXRA (0.57) | FABP3FABP4FABP5RXRARXRB | |
| SCHEMBL5839537 | 0.86 | FABP3 (0.67) | FABP3FABP4FABP5RXRARXRB | |
| SCHEMBL1305739 | 0.85 | PTGER1 (0.61) | FABP3FABP4FABP5PTGER1MEN1 | |
| SCHEMBL5839914 | 0.84 | FABP4 (0.88) | FABP3FABP4FABP5NR4A2PTGER1 | |
| SCHEMBL5663405 | 0.84 | FABP4 (0.88) | FABP3FABP4FABP5NR4A2PTGER1 | |
| SCHEMBL3814086 | 0.83 | PTGER1 (0.64) | RXRARXRBRXRGNR4A2PTGER1 | |
| SCHEMBL8980717 | 0.83 | ENPP2 (0.56) | RXRARXRBRXRGNR4A2PTGER1 | |
| SCHEMBL5839536 | 0.81 | FABP4 (1.00) | FABP3FABP4FABP5NR4A2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6984645-B2 | Dual inhibitors of adipocyte fatty acid binding protein and keratinocyte fatty acid binding protein | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-01-10 | — | — | US | disclosed |