Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17514981 | 0.77 | — | — | |
| SCHEMBL10428951 | 0.76 | BACE1 (0.36) | — | |
| SCHEMBL17514733 | 0.75 | ABL1 (0.44) | — | |
| SCHEMBL27482127 | 0.74 | BACE1 (0.34) | — | |
| SCHEMBL4250572 | 0.72 | ALDH1A1 (0.34) | — | |
| SCHEMBL27496672 | 0.71 | PTGS2 (0.41) | — | |
| SCHEMBL4279530 | 0.71 | HSD17B1 (0.45) | — | |
| SCHEMBL16485937 | 0.71 | CA9 (0.35) | — | |
| SCHEMBL27465816 | 0.71 | PTGS2 (0.36) | — | |
| SCHEMBL17514758 | 0.69 | NISCH (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7038077-B2 | Prodrugs of excitatory amino acids | ELI LILLY AND COMPANY (US) | 2006-05-02 | — | — | US | disclosed |
| US-20050009912-A1 | Prodrugs of excitatory amino acids | ELI LILLY AND COMPANY | 2005-01-13 | — | — | US | disclosed |
| US-20040138304-A1 | Prodrugs of excitatory amino acids | ELI LILLY AND COMPANY | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009912-A1 | Prodrugs of excitatory amino acids | SLC1A2, SLC1A3, SLC1A1 | NOTUM 3599/4885PGR 2764/4885 |
| US-20040138304-A1 | Prodrugs of excitatory amino acids | SLC1A2, SLC1A1, SLC1A3 | NOTUM 2683/4885PGR 2858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.