SCHEMBL5842412

SCHEMBL5842412

Cc1ccc(CC(=O)Cc2ccccc2)c(O)c1

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
GAA P10253 1/20 0.49
KMT2A Q03164 1/20 0.47
AKR1B1 P15121 2/20 0.46
LMNA P02545 1/20 0.44
PSMB8 P28062 1/20 0.44
PSMB5 P28074 1/20 0.44
SRC P12931 1/20 0.44
KCNMA1 Q12791 1/20 0.42
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
ALOX5 P09917 1/20 0.41
HTT P42858 1/20 0.41
CXCR2 P25025 1/20 0.41
CNR1 P21554 1/20 0.41
CNR2 P34972 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5841760 0.88 SRC (0.49) TDP1GAALMNASRCKCNMA1
SCHEMBL29481933 0.81 SRC (0.62) TDP1GAAKMT2AAKR1B1LMNA
SCHEMBL3228305 0.81 SRC (0.62) TDP1GAAKMT2AAKR1B1LMNA
SCHEMBL5841560 0.80 POLB (0.60) TDP1L3MBTL1GAALMNAHTT
SCHEMBL4031727 0.79 AKR1B1 (0.67) TDP1L3MBTL1GAAKMT2AAKR1B1
SCHEMBL11219229 0.79 L3MBTL1 (0.76) TDP1L3MBTL1KMT2AAKR1B1LMNA
SCHEMBL11181344 0.78 CTBP2 (0.60) TDP1L3MBTL1GAAAKR1B1LMNA
SCHEMBL31083107 0.78 ALOX5 (0.67) KMT2AALOX5
SCHEMBL8406693 0.76 TYR (0.46) TDP1L3MBTL1ALOX5
SCHEMBL9003695 0.75 SRC (0.49) TDP1GAAKMT2ALMNASRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6984716-B2 Phosphorus-containing compound CHANG CHUN PLASTICS CO., LTD. (TW) 2006-01-10 US disclosed
US-20040077825-A1 Phosphorus-containing compound CHANG CHUN PLASTICS CO., LTD. (TW) 2004-04-22 US disclosed