SCHEMBL5841560

SCHEMBL5841560

COc1ccc(CC(=O)Cc2ccccc2)c(O)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.60
TSHR P16473 2/20 0.52
MAOB P27338 1/20 0.49
ALDH1A1 P00352 3/20 0.49
LMNA P02545 1/20 0.49
CYP1A2 P05177 1/20 0.49
PGR P06401 1/20 0.49
CYP2D6 P10635 1/20 0.49
HPGD P15428 1/20 0.49
SLC6A2 P23975 1/20 0.49
PDE4A P27815 1/20 0.49
MAPK1 P28482 1/20 0.49
CYP2C19 P33261 1/20 0.49
HRH1 P35367 1/20 0.49
HTT P42858 1/20 0.49
SLC6A3 Q01959 1/20 0.49
PDE4D Q08499 1/20 0.49
USP2 O75604 1/20 0.48
PLAU P00749 1/20 0.48
ELANE P08246 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4026581 0.85 ALDH1A1 (0.59) POLBTSHRALDH1A1HSD17B10KDM4E
SCHEMBL30335932 0.82 POLB (0.73) POLBALDH1A1LMNACYP1A2PGR
SCHEMBL3296862 0.82 POLB (0.73) POLBALDH1A1LMNACYP1A2PGR
SCHEMBL28691182 0.81 POLB (0.62) POLBALDH1A1HPGDMAPK1RAB9A
SCHEMBL4032340 0.81 NPC1 (0.66) ALDH1A1HTTUSP2PLAUELANE
SCHEMBL6202473 0.81 POLB (0.61) POLBALDH1A1LMNACYP1A2PGR
SCHEMBL5842412 0.80 TDP1 (0.51) LMNAHTTGAATDP1L3MBTL1
SCHEMBL991232 0.80 L3MBTL1 (0.55) POLBLMNAHTTMAPTSMN1; SMN2
SCHEMBL11621845 0.80 CTBP2 (0.63) POLBMAOBLMNACYP1A2USP2
SCHEMBL30419864 0.80 ALOX5 (0.66) POLBTSHRMAOBALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105705131-B Cosmetic or dermatological composition comprising a merocyanine and a UV-screening agent 莱雅公司 2019-12-17 CN disclosed
US-6984716-B2 Phosphorus-containing compound CHANG CHUN PLASTICS CO., LTD. (TW) 2006-01-10 US disclosed
US-20040077825-A1 Phosphorus-containing compound CHANG CHUN PLASTICS CO., LTD. (TW) 2004-04-22 US disclosed