SCHEMBL58428

SCHEMBL58428

CCCCCCCCCCP(=O)(C(=O)c1c(Cl)cccc1Cl)C(=O)c1c(Cl)cccc1Cl

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PLK1 P53350 1/20 0.44
CETP P11597 6/20 0.43
HPGD P15428 1/20 0.41
ALDH1A1 P00352 2/20 0.41
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41
ATM Q13315 1/20 0.41
DRD3 P35462 1/20 0.40
LPAR3 Q9UBY5 3/20 0.39
LPAR2 Q9HBW0 1/20 0.39
ITGB1 P05556 1/20 0.39
ITGA4 P13612 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2769886 1.00 PLK1 (0.44) PLK1CETPHPGDALDH1A1MEN1
SCHEMBL7622733 1.00 PLK1 (0.44) PLK1CETPHPGDALDH1A1MEN1
SCHEMBL1087444 0.87 ALDH1A1 (0.44) PLK1HPGDALDH1A1MAPTDRD3
SCHEMBL5994155 0.87 TYK2 (0.42) PLK1HPGDALDH1A1DRD3ITGB1
SCHEMBL21300508 0.84 ALDH1A1 (0.41) PLK1HPGDALDH1A1DRD3
SCHEMBL5995028 0.83 MEN1 (0.40) PLK1HPGDMEN1KMT2ADRD3
SCHEMBL5996487 0.83 PPARA (0.44) PLK1HPGDDRD3ITGB1ITGA4
SCHEMBL6468590 0.83 CETP (0.44) CETPALDH1A1MEN1MAPTHTT
SCHEMBL6465547 0.83 CETP (0.44) CETPALDH1A1MEN1MAPTHTT
SCHEMBL6470028 0.83 CETP (0.44) CETPALDH1A1MEN1MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 316 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12024136-B2 Ultra-fast curing scratch-resistant headlight restoration coating ILLINOIS TOOL WORKS INC. (US) 2024-07-02 US claimed
EP-4286163-B1 ELECTRON BEAM CURABLE INK, AND IMAGE RECORDING METHOD FUJIFILM CORP (JP) 2026-04-01 EP disclosed
EP-4514304-B1 DENTAL COMPOSITION CONTAINING A RESORCINOL OR CATECHOL MOIETY CONTAINING COMPONENT AND USE THEREOF SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-03-25 EP disclosed
US-12577340-B2 Storage stable two-component dual cure dental composition SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-03-17 US disclosed
US-20260028440-A1 Curable Composition for Producing Transparent Orthodontic Attachments SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-01-29 US disclosed
EP-4681930-A1 IMAGE RECORDING METHOD, METHOD FOR MANUFACTURING LAMINATE, AND IMAGE RECORDING APPARATUS FUJIFILM Corporation (JP) 2026-01-21 EP disclosed
US-20250375971-A1 IMAGE RECORDING METHOD, MANUFACTURING METHOD OF LAMINATE, AND IMAGE RECORDING APPARATUS FUJIFILM CORP (JP) 2025-12-11 US disclosed
EP-4660262-A1 ACTIVE ENERGY RAY-CURABLE INKJET INK, ACTIVE ENERGY RAY-CURABLE INK SET, AND IMAGE RECORDING METHOD FUJIFILM Corporation (JP) 2025-12-10 EP disclosed
US-20250340747-A1 ACTIVE ENERGY RAY CURABLE TYPE INK JET INK, ACTIVE ENERGY RAY CURABLE TYPE INK SET, AND IMAGE RECORDING METHOD FUJIFILM CORP (JP) 2025-11-06 US disclosed
EP-4629958-A1 SURFACE-TREATED FILLER, DENTAL COMPOSITION CONTAINING SUCH A FILLER, PROCESS OF PRODUCTION AND USE THEREOF Solventum Intellectual Properties Company (US) 2025-10-15 EP disclosed
US-20080075882-A1 PROCESS FOR PRODUCING MOLDED PRINTED MATERIAL, AND MOLDED PRINTED MATERIAL FUJIFILM CORPORATION (JP) 2008-03-27 US disclosed
US-20070211111-A1 Ink composition, inkjet recording method, printed material, and process for producing lithographic printing plate FUJIFILM CORPORATION (JP) 2007-09-13 US disclosed
EP-1829680-A1 Ink composition, inkjet recording method, printed material, and process for producing lithographic printing plate FUJIFILM Corporation (JP) 2007-09-05 EP disclosed
EP-0825201-B2 Photocurable composition and curing process therefor SHOWA DENKO KK (JP) 2006-11-29 EP disclosed
US-7049350-B2 Polymerizable compound, polymerizable composition and cured product containing the compound SHOWA DENKO K.K. (JP) 2006-05-23 US disclosed
US-20040235980-A1 Polymerizable compound, polymerizable composition and cured product containing the compound SHOWA DENKO K.K. (JP) 2004-11-25 US disclosed
EP-0825201-B1 Photocurable composition and curing process therefor SHOWA DENKO KK (JP) 2002-02-27 EP disclosed
EP-0825201-A1 Photocurable composition and curing process therefor SHOWA DENKO KABUSHIKI KAISHA (JP) 1998-02-25 EP disclosed
US-4792632-A ADDITION POLYMER PHOTOINITIATORS ESPE FABRIK PHARMAZEUTISCHER PRAPARATE GMBH (DE) 1988-12-20 US disclosed
US-4737593-A PHOTOINITIATORS FOR ADDITION POLYMERIZATION; DENTISTRY Fabrik Pharmazeutischer Praparate (DE) 1988-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028440-A1 Curable Composition for Producing Transparent Orthodontic Attachments SMCHD1, SMC2, SMC1A PLK1 1473/4885CETP 3837/4885HPGD 4304/4885
US-12577340-B2 Storage stable two-component dual cure dental composition GPX4, SSRP1, H1-0 PLK1 4309/4885CETP 2795/4885HPGD 1741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.