Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 15/20 | 0.53 |
| ▸ | CTSL | P07711 | 14/20 | 0.53 |
| ▸ | CTSK | P43235 | 10/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3019566 | 0.84 | CTSS (0.39) | CTSSCTSLCTSKEPHX2EPHX1 | |
| SCHEMBL5841430 | 0.83 | CTSS (0.40) | CTSSCTSLCTSKKDM4EALDH1A1 | |
| SCHEMBL4800843 | 0.81 | CTSS (0.51) | CTSSCTSLCTSKKDM4EALDH1A1 | |
| SCHEMBL6685716 | 0.80 | KDM4E (0.47) | CTSSCTSLCTSKKDM4EALDH1A1 | |
| SCHEMBL3022158 | 0.79 | CTSS (0.49) | CTSSCTSLCTSK | |
| SCHEMBL5841440 | 0.78 | CTSS (0.64) | CTSSCTSLCTSKKDM4EALDH1A1 | |
| SCHEMBL5841433 | 0.78 | CTSS (0.64) | CTSSCTSLCTSKKDM4EALDH1A1 | |
| SCHEMBL6685637 | 0.76 | CTSK (0.41) | CTSSCTSLCTSKPOLBEPHX2 | |
| SCHEMBL5842460 | 0.76 | CTSS (0.42) | CTSSCTSLCTSKEPHX1 | |
| SCHEMBL22414310 | 0.75 | POLB (0.62) | CTSSCTSLCTSKKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7109243-B2 | Inhibitors of cathepsin S | IRM LLC (BM) | 2006-09-19 | — | — | US | claimed |