Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.41 |
| ▸ | CTSS | P25774 | 8/20 | 0.40 |
| ▸ | CTSL | P07711 | 6/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6686841 | 0.85 | CTSK (0.40) | CTSKPOLB | |
| SCHEMBL5404868 | 0.85 | CTSK (0.36) | CTSKCTSSKMT2AEPHX1 | |
| SCHEMBL5843360 | 0.76 | CTSS (0.53) | CTSKCTSSCTSLEPHX2POLB | |
| SCHEMBL5520748 | 0.72 | CYP3A4 (0.47) | EPHX2EPHX1 | |
| SCHEMBL5842740 | 0.71 | HTT (0.34) | — | |
| SCHEMBL6685642 | 0.68 | CTSS (0.54) | CTSKCTSSCTSLEPHX2POLB | |
| SCHEMBL6686917 | 0.68 | CTSS (0.54) | CTSKCTSSCTSLEPHX2POLB | |
| SCHEMBL3021858 | 0.68 | EPHX2 (0.57) | EPHX2POLBKMT2ACA12CA1 | |
| SCHEMBL9780251 | 0.67 | EPHX2 (0.56) | EPHX2POLBKMT2ACA12CA1 | |
| SCHEMBL5841440 | 0.66 | CTSS (0.64) | CTSKCTSSCTSLPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084842-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |