Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KYAT1 | Q16773 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17209749 | 0.86 | GAA (0.49) | NPSR1GAAALOX12MAPTATM | |
| SCHEMBL17803165 | 0.86 | NPSR1 (0.58) | NPSR1GAAALOX12MAPTATM | |
| SCHEMBL17803163 | 0.86 | NPSR1 (0.58) | NPSR1GAAALOX12MAPTATM | |
| SCHEMBL20642204 | 0.84 | NPSR1 (0.53) | NPSR1GAAALOX12MAPTATM | |
| SCHEMBL19831220 | 0.84 | GAA (0.65) | NPSR1GAAALOX12MAPTATM | |
| SCHEMBL20142642 | 0.84 | KYAT1 (0.60) | NPSR1GAAMAPTATMKYAT1 | |
| SCHEMBL20142641 | 0.84 | KYAT1 (0.60) | NPSR1GAAMAPTATMKYAT1 | |
| SCHEMBL20159628 | 0.84 | KYAT1 (0.60) | NPSR1GAAMAPTATMKYAT1 | |
| SCHEMBL28039654 | 0.84 | POLB (0.56) | NPSR1GAAMAPTATMKYAT1 | |
| SCHEMBL23354894 | 0.83 | NPSR1 (0.57) | NPSR1GAAALOX12MAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153815-B2 | Insecticide containing hydrazone derivative as the active ingredient and novel hydrazone derivative | NIHON NOHYAKU CO., LTD. (JP) | 2006-12-26 | — | — | US | disclosed |
| US-20050203149-A1 | Insecticide containing hydrazone derivatives as the active ingredient and novel hydrazone derivates | NIHON NOHYAKU CO., LTD (JP) | 2005-09-15 | — | — | US | disclosed |
| EP-1470752-A1 | INSECTICIDES CONTAINING HYDRAZONE DERIVATIVES AS THE ACTIVE INGREDIENT AND NOVEL HYDRAZONE DERIVATIVES | Nihon Nohyaku Co., Ltd. (JP) | 2004-10-27 | — | — | EP | disclosed |
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203149-A1 | Insecticide containing hydrazone derivatives as the active ingredient and novel hydrazone derivates | DDT, AOX1, HAX1 | NPSR1 2236/4885GAA 2767/4885ALOX12 1138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.