Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2231794 | 0.90 | ADRA2C (0.37) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| SCHEMBL2231523 | 0.77 | ADRA2C (0.40) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| SCHEMBL2232629 | 0.74 | ADRA2C (0.37) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| SCHEMBL6251581 | 0.73 | ADRA2C (0.36) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| SCHEMBL22879574 | 0.73 | ADRA2C (0.40) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| SCHEMBL9250186 | 0.73 | ALDH1A1 (0.39) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| SCHEMBL5175634 | 0.72 | GPR3 (0.46) | — | |
| SCHEMBL2234349 | 0.72 | HTR2A (0.37) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| SCHEMBL8160683 | 0.72 | ADRA2C (0.40) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| SCHEMBL6251445 | 0.72 | ADRA2C (0.37) | ADRA2CPTGS2HRH1HTR3APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060252895-A1 | Metallocene compounds and use thereof in catalysts for the polymerization of olefins | BASELL TECHNOLOGY COMPANY B.V. | 2006-11-09 | — | — | US | disclosed |
| US-7094847-B2 | Metallocene compounds and use thereof in catalysts for the polymerization of olefins | BASELL TECHNOLOGY COMPANY B.V. (NL) | 2006-08-22 | — | — | US | disclosed |
| EP-0702687-B1 | METALLOCENE COMPOUNDS AND USE THEREOF IN CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | BASELL TECHNOLOGY CO BV (NL) | 2001-12-05 | — | — | EP | disclosed |
| US-20010012877-A1 | Metallocene compounds and use thereof in catalysts for the polymerization of olefins | MONTELL TECHNOLOGY COMPANY B.V. | 2001-08-09 | — | — | US | disclosed |
| US-6211108-B1 | Metallocene compounds and use thereof in catalysts for the polymerization of olefins | MONTELL TECHNOLOGY COMPANY BV (NL) | 2001-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252895-A1 | Metallocene compounds and use thereof in catalysts for the polymerization of olefins | CPNE4, OR10J3, ORC3 | ADRA2C 4321/4885PTGS2 572/4885HRH1 3534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.