Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NAAA | Q02083 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | MLNR | O43193 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5843353 | 0.98 | ALDH1A1 (0.52) | ALDH1A1NAAASMN1; SMN2RAB9AMAPT | |
| SCHEMBL7746812 | 0.89 | SMN1; SMN2 (0.62) | ALDH1A1NAAASMN1; SMN2RAB9AMAPT | |
| SCHEMBL17296564 | 0.89 | NAAA (0.60) | ALDH1A1NAAASMN1; SMN2RAB9AMAPT | |
| SCHEMBL23120693 | 0.86 | NAAA (0.71) | ALDH1A1NAAASMN1; SMN2RAB9AMAPT | |
| SCHEMBL29663742 | 0.86 | NAAA (0.71) | ALDH1A1NAAASMN1; SMN2RAB9AMAPT | |
| SCHEMBL17686363 | 0.86 | NAAA (0.71) | ALDH1A1NAAASMN1; SMN2RAB9AMAPT | |
| SCHEMBL26127863 | 0.86 | NAAA (0.71) | ALDH1A1NAAASMN1; SMN2RAB9AMAPT | |
| SCHEMBL31404784 | 0.86 | NAAA (0.71) | ALDH1A1NAAASMN1; SMN2RAB9AMAPT | |
| SCHEMBL27826248 | 0.85 | SMN1; SMN2 (0.61) | ALDH1A1NAAASMN1; SMN2RAB9AMAPT | |
| SCHEMBL16897737 | 0.85 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2RAB9AMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040127564-A1 | Derivatives of butyric acid and uses thereof | THE UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES | 2004-07-01 | — | — | US | claimed |
| US-20020143056-A1 | Derivatives of butyric acid and uses thereof | THE UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES | 2002-10-03 | — | — | US | claimed |
| WO-2000073257-A1 | DERIVATIVES OF BUTYRIC ACID AND USES THEREOF | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2000-12-07 | — | — | WO | claimed |
| CN-104860920-A | Alcaftadine intermediate preparation method | WUHAN WUYAO SCIENCE & TECHNOLOGY CO LTD | 2015-08-26 | — | — | CN | disclosed |
| US-7034020-B2 | Derivatives of butyric acid and uses thereof | THE UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCE (US) | 2006-04-25 | — | — | US | disclosed |
| US-20040127564-A1 | Derivatives of butyric acid and uses thereof | THE UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES | 2004-07-01 | — | — | US | disclosed |
| US-6664394-B2 | As inactivator of antigen- specific T cells is useful in the prophylaxis or therapy of autoimmune diseases, disorders involving an autoimmune component or neoplastic diseases | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS | 2003-12-16 | — | — | US | disclosed |
| US-20020143056-A1 | Derivatives of butyric acid and uses thereof | THE UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES | 2002-10-03 | — | — | US | disclosed |
| US-6407107-B1 | 4-(MORPHOLINO)ALKYL BUTANAMIDE DERIVATIVES; AUTOIMMUNE DISEASES; ANTICARCINOGENIC AGENTS | THE BOARD OF TRUSTEES OF THE UNVERSITY OF ARKANSAS | 2002-06-18 | — | — | US | disclosed |
| WO-2000073257-A1 | DERIVATIVES OF BUTYRIC ACID AND USES THEREOF | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2000-12-07 | — | — | WO | disclosed |
| US-5492919-A | IRRITABLE BOWEL DISORDER | SMITHKLINE BEECHAM P.L.C. (GB) | 1996-02-20 | — | — | US | disclosed |
| EP-0596933-A1 | 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-05-18 | — | — | EP | disclosed |
| WO-1993002677-A1 | 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020143056-A1 | Derivatives of butyric acid and uses thereof | CD4, NFATC1, GABRA4 | ALDH1A1 858/4885NAAA 1282/4885SMN1; SMN2 2088/4885 |
| US-20040127564-A1 | Derivatives of butyric acid and uses thereof | CD4, NFATC1, GABRA4 | ALDH1A1 849/4885NAAA 1261/4885SMN1; SMN2 2008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.