Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 3/20 | 0.55 |
| ▸ | CTSS | P25774 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6705839 | 0.79 | KLK7 (0.53) | KLK7CTSSALDH1A1CTSL | |
| SCHEMBL3011519 | 0.78 | CTSS (0.70) | CTSSPOLBRAB9ASMN1; SMN2CTSL | |
| SCHEMBL3011513 | 0.78 | CTSS (0.70) | CTSSPOLBRAB9ASMN1; SMN2CTSL | |
| SCHEMBL5329436 | 0.77 | KLK7 (0.48) | KLK7CTSSPOLBRAB9ASMN1; SMN2 | |
| SCHEMBL3017458 | 0.75 | CTSS (0.59) | CTSSCTSL | |
| SCHEMBL27667422 | 0.75 | CTSS (0.44) | KLK7CTSSHPGDKMT2APOLB | |
| SCHEMBL3018438 | 0.75 | CTSS (0.66) | KLK7CTSSPOLBRAB9ASMN1; SMN2 | |
| SCHEMBL20725809 | 0.72 | ALDH1A1 (0.67) | HPGDKMT2APOLBALDH1A1 | |
| SCHEMBL5844661 | 0.72 | CTSS (0.50) | KLK7CTSSRAB9ACTSL | |
| SCHEMBL4621542 | 0.72 | NAMPT (0.46) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7109243-B2 | Inhibitors of cathepsin S | IRM LLC (BM) | 2006-09-19 | — | — | US | claimed |