Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7846887 | 0.74 | ALDH1A1 (0.39) | ALDH1A1KDM4EGAAKMT2ATSHR | |
| SCHEMBL7568404 | 0.74 | ALDH1A1 (0.43) | ALDH1A1KDM4EGAAKMT2ATSHR | |
| SCHEMBL7563366 | 0.73 | ALDH1A1 (0.42) | ALDH1A1KDM4EGAAKMT2ATSHR | |
| SCHEMBL7155796 | 0.73 | PTPN2 (0.43) | ALDH1A1KDM4EGAAKMT2ACYP1A2 | |
| SCHEMBL7564276 | 0.73 | CYP1A2 (0.39) | ALDH1A1KDM4EGAAKMT2ACYP1A2 | |
| SCHEMBL7127946 | 0.72 | ALDH1A1 (0.43) | ALDH1A1KDM4EGAAKMT2ACYP1A2 | |
| SCHEMBL7862333 | 0.72 | ALDH1A1 (0.47) | ALDH1A1KDM4EGAAKMT2ATSHR | |
| SCHEMBL5843765 | 0.71 | ALDH1A1 (0.38) | ALDH1A1KDM4EGAAKMT2ACYP1A2 | |
| SCHEMBL7864191 | 0.71 | ALDH1A1 (0.36) | ALDH1A1KDM4EGAAKMT2ACYP1A2 | |
| SCHEMBL6225735 | 0.71 | ALDH1A1 (0.37) | ALDH1A1KDM4ECYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7019026-B1 | Modulators of Protein Tyrosine Phosphatases (PTPases) | NOVO NORDISK A/S (DK) | 2006-03-28 | — | — | US | disclosed |