Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6316711 | 0.77 | CYP1A2 (0.44) | ALDH1A1CYP2C9CYP1A2CYP2C19ADORA1 | |
| SCHEMBL7681582 | 0.77 | EPHX2 (0.38) | ALDH1A1CYP2C9CYP1A2CYP2C19GAA | |
| SCHEMBL5844714 | 0.72 | ALDH1A1 (0.40) | ALDH1A1CYP2C9CYP1A2CYP2C19GAA | |
| SCHEMBL9170071 | 0.71 | CYP2C9 (0.59) | ALDH1A1CYP2C9CYP1A2CYP2C19CASP1 | |
| SCHEMBL7861190 | 0.70 | CYP1A2 (0.42) | ALDH1A1CYP2C9CYP1A2CYP2C19ADORA1 | |
| SCHEMBL6049947 | 0.69 | ADORA1 (0.44) | ALDH1A1CYP2C9CYP1A2CYP2C19ADORA1 | |
| SCHEMBL7490590 | 0.67 | KEAP1 (0.45) | ALDH1A1ADORA1KEAP1NFE2L2 | |
| SCHEMBL8858326 | 0.67 | ALDH1A1 (0.47) | ALDH1A1CYP2C9CYP1A2CYP2C19GAA | |
| SCHEMBL5838365 | 0.66 | CYP1A2 (0.40) | ALDH1A1CYP2C9CYP1A2CYP2C19ADORA1 | |
| SCHEMBL7004595 | 0.66 | ADORA1 (0.40) | ALDH1A1CYP2C19ADORA1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030069267-A1 | Modulators of protein tyrosine phosphatases (PTPases) | MOLLER NIELS PETER HUNDAHL (DK) | 2003-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069267-A1 | Modulators of protein tyrosine phosphatases (PTPases) | PTPRCAP, PTPRS, PTPRA | ALDH1A1 3737/4885CYP2C9 3024/4885CYP1A2 1107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.