Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.65 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | FDPS | P14324 | 1/20 | 0.58 |
| ▸ | TTR | P02766 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TACR2 | P21452 | 1/20 | 0.57 |
| ▸ | APP | P05067 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29377794 | 1.00 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2PDCD1CD274TSHR | |
| SCHEMBL161066 | 0.94 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2PDCD1CD274TSHR | |
| SCHEMBL7784719 | 0.92 | PDCD1 (0.74) | ALDH1A1SMN1; SMN2PDCD1CD274TSHR | |
| SCHEMBL584489 | 0.91 | TACR2 (0.62) | ALDH1A1SMN1; SMN2PDCD1CD274MAPT | |
| SCHEMBL29446267 | 0.91 | TACR2 (0.62) | ALDH1A1SMN1; SMN2PDCD1CD274MAPT | |
| SCHEMBL19658009 | 0.89 | FDPS (0.65) | ALDH1A1SMN1; SMN2PDCD1CD274MAPT | |
| SCHEMBL2463491 | 0.89 | NPC1 (0.63) | ALDH1A1SMN1; SMN2PDCD1CD274MAPT | |
| SCHEMBL9587052 | 0.88 | CYP1A1 (0.65) | ALDH1A1PDCD1CD274AMY1AHTT | |
| SCHEMBL9587050 | 0.88 | CYP1A1 (0.65) | ALDH1A1PDCD1CD274AMY1AHTT | |
| SCHEMBL8698472 | 0.88 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2PDCD1CD274TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 790 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10751330-B2 | Human therapeutic agents | ANKH LIFE SCIENCES LIMITED (IE) | 2020-08-25 | — | — | US | claimed |
| US-20200147061-A1 | HUMAN THERAPEUTIC AGENTS | ANKH LIFE SCIENCES LIMITED (IE) | 2020-05-14 | — | — | US | claimed |
| US-10092550-B2 | Therapeutic compositions containing curcumin, harmine, and isovanillin components, and methods of use thereof | IONS PHARMACEUTICAL S.À R.L. (LU) | 2018-10-09 | — | — | US | claimed |
| US-20170105975-A1 | THERAPEUTIC COMPOSITIONS CONTAINING HARMINE AND ISOVANILLIN COMPONENTS, AND METHODS OF USE THEREOF | IONS PHARMACEUTICAL S.À R.L. (LU) | 2017-04-20 | — | — | US | claimed |
| US-20170042865-A1 | THERAPEUTIC COMPOSITIONS CONTAINING CURCUMIN, HARMINE, AND ISOVANILLIN COMPONENTS, AND METHODS OF USE THEREOF | IONS PHARMACEUTICAL S.À R.L. (LU) | 2017-02-16 | — | — | US | claimed |
| US-9512063-B2 | Process for the preparation of advantame | DIVI'S LABORATORIES LIMITED (IN) | 2016-12-06 | — | — | US | claimed |
| WO-2016181220-A2 | THERAPEUTIC COMPOSITIONS AND METHODS OF USE THEREOF | IONS PHARMACEUTICAL S.À R.L. (LU) | 2016-11-17 | — | — | WO | claimed |
| US-20160304439-A1 | PROCESS FOR THE PREPARATION OF ADVANTAME | DIVI'S LABORATORIES LIMITED (IN) | 2016-10-20 | — | — | US | claimed |
| CN-103980152-B | Benzamide compounds with anti-tumor activity and its preparation method and application | XI'AN JIAOTONG UNIVERSITY (CN) | 2016-04-27 | — | — | CN | claimed |
| CN-103980153-B | Dibenzoyl amine compound with anti-tumor activity and its preparation method and application | XI'AN JIAOTONG UNIVERSITY (CN) | 2016-01-20 | — | — | CN | claimed |
| US-20090278087-A1 | Oxygen Scavenging Compositions and Packaging Comprising Said Compositions | CONSTAR INTERNATIONAL, INC (US) | 2009-11-12 | — | — | US | claimed |
| CN-101193976-A | Oxygen scavenging compositions and packages comprising the same | CONSTAR INT INC (US) | 2008-06-04 | — | — | CN | claimed |
| EP-1848659-A2 | OXYGEN SCAVENGING COMPOSITIONS AND PACKAGING COMPRISING SAID COMPOSITIONS | Constar International Inc. (US) | 2007-10-31 | — | — | EP | claimed |
| WO-2006088889-A2 | OXYGEN SCAVENGING COMPOSITIONS AND PACKAGING COMPRISING SAID COMPOSITIONS | CONSTAR INTERNATIONAL, INC. (US) | 2006-08-24 | — | — | WO | claimed |
| US-20060180790-A1 | polyesters; melt polymerization; packaging | CONSTAR INTERNATIONAL INC. (US) | 2006-08-17 | — | — | US | claimed |
| US-20060084176-A1 | Detection of uronium salts | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2006-04-20 | — | — | US | claimed |
| EP-0674232-B1 | Recording sheets | XEROX CORP (US) | 2000-05-31 | — | — | EP | claimed |
| US-5931995-A | Ink compositions | XEROX CORPORATION (US) | 1999-08-03 | — | — | US | claimed |
| US-5663022-A | Recording sheets | XEROX CORPORATION (US) | 1997-09-02 | — | — | US | claimed |
| EP-0674232-A2 | Recording sheets | XEROX CORPORATION (US) | 1995-09-27 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10751330-B2 | Human therapeutic agents | INMT, HNMT, HASPIN | ALDH1A1 371/4885SMN1; SMN2 2552/4885PDCD1 1538/4885 |
| US-20170042865-A1 | THERAPEUTIC COMPOSITIONS CONTAINING CURCUMIN, HARMINE, AND ISOVANILLIN COMPONENTS, AND METHODS OF USE THEREOF | INMT, HNMT, CPT1A | ALDH1A1 460/4885SMN1; SMN2 3486/4885PDCD1 2048/4885 |
| US-10092550-B2 | Therapeutic compositions containing curcumin, harmine, and isovanillin components, and methods of use thereof | INMT, HNMT, CPT1A | ALDH1A1 460/4885SMN1; SMN2 3486/4885PDCD1 2048/4885 |
| US-20160304439-A1 | PROCESS FOR THE PREPARATION OF ADVANTAME | TASP1, ASPH, COMT | ALDH1A1 312/4885SMN1; SMN2 1642/4885PDCD1 3151/4885 |
| US-20090278087-A1 | Oxygen Scavenging Compositions and Packaging Comprising Said Compositions | LPO, GPX4, PRDX3 | ALDH1A1 548/4885SMN1; SMN2 651/4885PDCD1 2777/4885 |
| US-20170105975-A1 | THERAPEUTIC COMPOSITIONS CONTAINING HARMINE AND ISOVANILLIN COMPONENTS, AND METHODS OF USE THEREOF | INMT, HNMT, COMT | ALDH1A1 320/4885SMN1; SMN2 3053/4885PDCD1 2177/4885 |
| US-20200147061-A1 | HUMAN THERAPEUTIC AGENTS | INMT, HNMT, HASPIN | ALDH1A1 371/4885SMN1; SMN2 2552/4885PDCD1 1538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.